Kinetic and dynamic computational model-based characterization of new proteins in mice: application to interferon alpha linked to apolipoprotein A-I.

Interferon alpha linked to apolipoprotein A-I has been recently proposed as an improved interferon-based therapy. In the present study, we aimed to develop a computational model to gain further insight into the in vivo behaviour of this new fusion protein. In order to facilitate in vivo evaluation o...

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Autores principales: Zinnia Patricia Parra-Guillen, Jessica Fioravanti, Jose Medina-Echeverz, Celia Gomar, Nuria Ardaiz, Iñaki F Troconiz, Pedro Berraondo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/b9c8a9547a1a4ebb8f25d94d2779164c
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