Two distinct integrin-mediated mechanisms contribute to apical lumen formation in epithelial cells.

<h4>Background</h4>Formation of apical compartments underlies the morphogenesis of most epithelial organs during development. The extracellular matrix (ECM), particularly the basement membrane (BM), plays an important role in orienting the apico-basal polarity and thereby the positioning...

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Autores principales: Satu Marja Myllymäki, Terhi Piritta Teräväinen, Aki Manninen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/b9ca3b83039b4089b04f565d297fa11a
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