Exploring the translational disconnect between the murine and human inflammatory response: analysis of LPS dose–response relationship in murine versus human cell lines and implications for translation into murine models of sepsis
Eamon P McCarron,1 Dominic P Williams,1 Daniel J Antoine,1 Anja Kipar,2 Jana Lemm,3 Sebastian Stehr,3 Ingeborg D Welters,4 1Department of Clinical and Molecular Pharmacology, Centre for Drug Safety Science, Institute of Translational Medicine, 2Department of Veterinary Pathology, University of Liver...
Guardado en:
Autores principales: | McCarron EP, Williams DP, Antoine DJ, Kipar A, Lemm J, Stehr S, Welters ID |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Dove Medical Press
2015
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b9cb993ed03e420fbcb839c30cb460c1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Transcriptomic insight into the translational value of two murine models in human atopic dermatitis
por: Young-Won Kim, et al.
Publicado: (2021) -
Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
por: Xuhua Tang, et al.
Publicado: (2016) -
Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
por: Brice Lagrange, et al.
Publicado: (2018) -
Humanization and characterization of an anti-human TNF-α murine monoclonal antibody.
por: Wei-Chun Chiu, et al.
Publicado: (2011) -
Reducing Animal Use with a Biotelemetry-Enhanced Murine Model of Sepsis
por: Anthony Lewis, et al.
Publicado: (2017)