Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.

This study evaluates the effect of local infiltration analgesia with bupivacaine and adrenaline on perioperative blood loss in total hip arthroplasty. Patients who had primary total hip arthroplasty were retrospectively assigned to two groups. One group had 100 ml of bupivacaine/adrenaline solution...

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Autores principales:	Marcin Ceynowa, Tomasz Sikora, Marek Rocławski, Mariusz Treder, Krzysztof Kolarz, Rafał Pankowski, Tomasz Mazurek
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b9ce403d4ab5489db8dd1a2523b2ff02
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spelling	oai:doaj.org-article:b9ce403d4ab5489db8dd1a2523b2ff022021-12-02T20:06:21ZLocal infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.1932-620310.1371/journal.pone.0257202https://doaj.org/article/b9ce403d4ab5489db8dd1a2523b2ff022021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257202https://doaj.org/toc/1932-6203This study evaluates the effect of local infiltration analgesia with bupivacaine and adrenaline on perioperative blood loss in total hip arthroplasty. Patients who had primary total hip arthroplasty were retrospectively assigned to two groups. One group had 100 ml of bupivacaine/adrenaline solution injected into periarticular soft tissues at the end of the procedure. There were 55 patients in the infiltrated hip group and 44 patients in the not infiltrated group. Patients' hemoglobin level (Hb), hematocrit (HTC), red blood count (RBC), platelet count (PLT) and International Normalized Ratio (INR) as well as the need for blood transfusions were compared statistically between groups preoperatively and postoperatively. There were no significant differences between Hb, HTC or RBC levels as well as the rate and amount of blood transfusions on the 1st, 4th postoperative days or at patients' discharge between infiltrated and not infiltrated groups. This study does not support the hypothesis that the use of local infiltration analgesia with adrenaline may reduce perioperative blood loss in total hip arthroplasty.Marcin CeynowaTomasz SikoraMarek RocławskiMariusz TrederKrzysztof KolarzRafał PankowskiTomasz MazurekPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0257202 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Marcin Ceynowa Tomasz Sikora Marek Rocławski Mariusz Treder Krzysztof Kolarz Rafał Pankowski Tomasz Mazurek Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.
description	This study evaluates the effect of local infiltration analgesia with bupivacaine and adrenaline on perioperative blood loss in total hip arthroplasty. Patients who had primary total hip arthroplasty were retrospectively assigned to two groups. One group had 100 ml of bupivacaine/adrenaline solution injected into periarticular soft tissues at the end of the procedure. There were 55 patients in the infiltrated hip group and 44 patients in the not infiltrated group. Patients' hemoglobin level (Hb), hematocrit (HTC), red blood count (RBC), platelet count (PLT) and International Normalized Ratio (INR) as well as the need for blood transfusions were compared statistically between groups preoperatively and postoperatively. There were no significant differences between Hb, HTC or RBC levels as well as the rate and amount of blood transfusions on the 1st, 4th postoperative days or at patients' discharge between infiltrated and not infiltrated groups. This study does not support the hypothesis that the use of local infiltration analgesia with adrenaline may reduce perioperative blood loss in total hip arthroplasty.
format	article
author	Marcin Ceynowa Tomasz Sikora Marek Rocławski Mariusz Treder Krzysztof Kolarz Rafał Pankowski Tomasz Mazurek
author_facet	Marcin Ceynowa Tomasz Sikora Marek Rocławski Mariusz Treder Krzysztof Kolarz Rafał Pankowski Tomasz Mazurek
author_sort	Marcin Ceynowa
title	Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.
title_short	Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.
title_full	Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.
title_fullStr	Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.
title_full_unstemmed	Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.
title_sort	local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/b9ce403d4ab5489db8dd1a2523b2ff02
work_keys_str_mv	AT marcinceynowa localinfiltrationanalgesiawithbupivacaineandadrenalinedoesnotreduceperioperativebloodlossintotalhiparthroplasty AT tomaszsikora localinfiltrationanalgesiawithbupivacaineandadrenalinedoesnotreduceperioperativebloodlossintotalhiparthroplasty AT marekrocławski localinfiltrationanalgesiawithbupivacaineandadrenalinedoesnotreduceperioperativebloodlossintotalhiparthroplasty AT mariusztreder localinfiltrationanalgesiawithbupivacaineandadrenalinedoesnotreduceperioperativebloodlossintotalhiparthroplasty AT krzysztofkolarz localinfiltrationanalgesiawithbupivacaineandadrenalinedoesnotreduceperioperativebloodlossintotalhiparthroplasty AT rafałpankowski localinfiltrationanalgesiawithbupivacaineandadrenalinedoesnotreduceperioperativebloodlossintotalhiparthroplasty AT tomaszmazurek localinfiltrationanalgesiawithbupivacaineandadrenalinedoesnotreduceperioperativebloodlossintotalhiparthroplasty
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Local infiltration analgesia with bupivacaine and adrenaline does not reduce perioperative blood loss in total hip arthroplasty.

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