The telomere complex and the origin of the cancer stem cell

Abstract Exquisite regulation of telomere length is essential for the preservation of the lifetime function and self-renewal of stem cells. However, multiple oncogenic pathways converge on induction of telomere attrition or telomerase overexpression and these events can by themselves trigger maligna...

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Bibliographic Details
Main Author: A. Torres-Montaner
Format: article
Language:EN
Published: BMC 2021
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Online Access:https://doaj.org/article/b9d99a7caf15421fbad10efff3aadd3b
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