Validity of the patient health questionnaire 9-item in autistic youths: a pilot study

Abstract Background Autistic adolescents have greater predisposition to depression and suicidality than neurotypical adolescents. Early detection is essential for timely treatment. The Patient Health Questionnaire 9-item (PHQ-9) is a brief screen for depression. The study examines the validity of th...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Thanita Pilunthanakul, Tze Jui Goh, Daniel Shuen Sheng Fung, Rehena Sultana, John Carson Allen, Min Sung
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Depression adolescent PHQ-9 autism ROC Psychiatry RC435-571
Acceso en línea:	https://doaj.org/article/b9dd6a3e981041cd88fefb6727ac8380
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b9dd6a3e981041cd88fefb6727ac8380
record_format	dspace
spelling	oai:doaj.org-article:b9dd6a3e981041cd88fefb6727ac83802021-11-14T12:08:25ZValidity of the patient health questionnaire 9-item in autistic youths: a pilot study10.1186/s12888-021-03556-w1471-244Xhttps://doaj.org/article/b9dd6a3e981041cd88fefb6727ac83802021-11-01T00:00:00Zhttps://doi.org/10.1186/s12888-021-03556-whttps://doaj.org/toc/1471-244XAbstract Background Autistic adolescents have greater predisposition to depression and suicidality than neurotypical adolescents. Early detection is essential for timely treatment. The Patient Health Questionnaire 9-item (PHQ-9) is a brief screen for depression. The study examines the validity of the PHQ-9 for detecting major depressive disorder (MDD) in autistic youths. Methods English speaking youths aged 10–18 years, with DSM-IV/DSM-5/ICD-10 diagnosis of Autism Spectrum Disorder (ASD), and their parents presenting to a child psychiatric service were invited to participate between May 2018 to August 2020. Participants completed the respective self- and parent-rated PHQ-9 independently. MDD was verified using the MINI-Kid (Mini-International Neuropsychiatric Interview, Kid version). Results One hundred one youth, mean (SD) age 14.6 (2.3), were enrolled. 27 (27%) met criteria for current MDD. Mean total PHQ-9 scores, percentage ratings for severity of symptoms of depression, functional impairment, dysthymia and suicidality were compared. Areas under the ROC curve and statistically optimal cutoffs were determined. Parents rated depressive symptoms severity lower than their children. The PHQ-9 displayed low sensitivity with high false negative rates at conventional, adjusted and proposed cutoffs. Conclusions Future studies should improve on the validity and reliability of existing depression screening tools, or develop more appropriate screening methods of depression, for autistic youths.Thanita PilunthanakulTze Jui GohDaniel Shuen Sheng FungRehena SultanaJohn Carson AllenMin SungBMCarticleDepression adolescent PHQ-9 autism ROCPsychiatryRC435-571ENBMC Psychiatry, Vol 21, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Depression adolescent PHQ-9 autism ROC Psychiatry RC435-571
spellingShingle	Depression adolescent PHQ-9 autism ROC Psychiatry RC435-571 Thanita Pilunthanakul Tze Jui Goh Daniel Shuen Sheng Fung Rehena Sultana John Carson Allen Min Sung Validity of the patient health questionnaire 9-item in autistic youths: a pilot study
description	Abstract Background Autistic adolescents have greater predisposition to depression and suicidality than neurotypical adolescents. Early detection is essential for timely treatment. The Patient Health Questionnaire 9-item (PHQ-9) is a brief screen for depression. The study examines the validity of the PHQ-9 for detecting major depressive disorder (MDD) in autistic youths. Methods English speaking youths aged 10–18 years, with DSM-IV/DSM-5/ICD-10 diagnosis of Autism Spectrum Disorder (ASD), and their parents presenting to a child psychiatric service were invited to participate between May 2018 to August 2020. Participants completed the respective self- and parent-rated PHQ-9 independently. MDD was verified using the MINI-Kid (Mini-International Neuropsychiatric Interview, Kid version). Results One hundred one youth, mean (SD) age 14.6 (2.3), were enrolled. 27 (27%) met criteria for current MDD. Mean total PHQ-9 scores, percentage ratings for severity of symptoms of depression, functional impairment, dysthymia and suicidality were compared. Areas under the ROC curve and statistically optimal cutoffs were determined. Parents rated depressive symptoms severity lower than their children. The PHQ-9 displayed low sensitivity with high false negative rates at conventional, adjusted and proposed cutoffs. Conclusions Future studies should improve on the validity and reliability of existing depression screening tools, or develop more appropriate screening methods of depression, for autistic youths.
format	article
author	Thanita Pilunthanakul Tze Jui Goh Daniel Shuen Sheng Fung Rehena Sultana John Carson Allen Min Sung
author_facet	Thanita Pilunthanakul Tze Jui Goh Daniel Shuen Sheng Fung Rehena Sultana John Carson Allen Min Sung
author_sort	Thanita Pilunthanakul
title	Validity of the patient health questionnaire 9-item in autistic youths: a pilot study
title_short	Validity of the patient health questionnaire 9-item in autistic youths: a pilot study
title_full	Validity of the patient health questionnaire 9-item in autistic youths: a pilot study
title_fullStr	Validity of the patient health questionnaire 9-item in autistic youths: a pilot study
title_full_unstemmed	Validity of the patient health questionnaire 9-item in autistic youths: a pilot study
title_sort	validity of the patient health questionnaire 9-item in autistic youths: a pilot study
publisher	BMC
publishDate	2021
url	https://doaj.org/article/b9dd6a3e981041cd88fefb6727ac8380
work_keys_str_mv	AT thanitapilunthanakul validityofthepatienthealthquestionnaire9iteminautisticyouthsapilotstudy AT tzejuigoh validityofthepatienthealthquestionnaire9iteminautisticyouthsapilotstudy AT danielshuenshengfung validityofthepatienthealthquestionnaire9iteminautisticyouthsapilotstudy AT rehenasultana validityofthepatienthealthquestionnaire9iteminautisticyouthsapilotstudy AT johncarsonallen validityofthepatienthealthquestionnaire9iteminautisticyouthsapilotstudy AT minsung validityofthepatienthealthquestionnaire9iteminautisticyouthsapilotstudy
_version_	1718429427573981184

Validity of the patient health questionnaire 9-item in autistic youths: a pilot study

Ejemplares similares