Essential role for a novel population of binucleated mammary epithelial cells in lactation

The main function of the mammary gland is to produce milk to sustain offspring. Here, the authors show that secretory alveolar cells in the lactating gland in several species are binucleated, which increases milk production, and that binucleation is regulated by Aurora kinase-A and Polo-like kinase-...

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Autores principales:	Anne C. Rios, Nai Yang Fu, Paul R. Jamieson, Bhupinder Pal, Lachlan Whitehead, Kevin R. Nicholas, Geoffrey J. Lindeman, Jane E. Visvader
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b9df98d6e85146f8b1f32303442dfa3f
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spelling	oai:doaj.org-article:b9df98d6e85146f8b1f32303442dfa3f2021-12-02T14:39:30ZEssential role for a novel population of binucleated mammary epithelial cells in lactation10.1038/ncomms114002041-1723https://doaj.org/article/b9df98d6e85146f8b1f32303442dfa3f2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11400https://doaj.org/toc/2041-1723The main function of the mammary gland is to produce milk to sustain offspring. Here, the authors show that secretory alveolar cells in the lactating gland in several species are binucleated, which increases milk production, and that binucleation is regulated by Aurora kinase-A and Polo-like kinase-1.Anne C. RiosNai Yang FuPaul R. JamiesonBhupinder PalLachlan WhiteheadKevin R. NicholasGeoffrey J. LindemanJane E. VisvaderNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anne C. Rios Nai Yang Fu Paul R. Jamieson Bhupinder Pal Lachlan Whitehead Kevin R. Nicholas Geoffrey J. Lindeman Jane E. Visvader Essential role for a novel population of binucleated mammary epithelial cells in lactation
description	The main function of the mammary gland is to produce milk to sustain offspring. Here, the authors show that secretory alveolar cells in the lactating gland in several species are binucleated, which increases milk production, and that binucleation is regulated by Aurora kinase-A and Polo-like kinase-1.
format	article
author	Anne C. Rios Nai Yang Fu Paul R. Jamieson Bhupinder Pal Lachlan Whitehead Kevin R. Nicholas Geoffrey J. Lindeman Jane E. Visvader
author_facet	Anne C. Rios Nai Yang Fu Paul R. Jamieson Bhupinder Pal Lachlan Whitehead Kevin R. Nicholas Geoffrey J. Lindeman Jane E. Visvader
author_sort	Anne C. Rios
title	Essential role for a novel population of binucleated mammary epithelial cells in lactation
title_short	Essential role for a novel population of binucleated mammary epithelial cells in lactation
title_full	Essential role for a novel population of binucleated mammary epithelial cells in lactation
title_fullStr	Essential role for a novel population of binucleated mammary epithelial cells in lactation
title_full_unstemmed	Essential role for a novel population of binucleated mammary epithelial cells in lactation
title_sort	essential role for a novel population of binucleated mammary epithelial cells in lactation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b9df98d6e85146f8b1f32303442dfa3f
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Essential role for a novel population of binucleated mammary epithelial cells in lactation

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