OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM

Presently, the expressed tendency to deterioration in parameters of semen is noted in the world, at the same time both the quantity of spermatozoa, and their functional properties decrease. The spermatogenesis is a difficult, extremely sensible process of cellular differentiation; the different syst...

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Autores principales:	E. A. Kirilenko, V. F. Onopko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	oxidative stress reactive oxygen species male infertility antioxidant Science Q
Acceso en línea:	https://doaj.org/article/b9e7d0867d244706952add2a20d88dc0
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spelling	oai:doaj.org-article:b9e7d0867d244706952add2a20d88dc02021-11-23T06:14:37ZOXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM2541-94202587-959610.12737/article_59a614fd84d146.40261567https://doaj.org/article/b9e7d0867d244706952add2a20d88dc02017-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/628https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Presently, the expressed tendency to deterioration in parameters of semen is noted in the world, at the same time both the quantity of spermatozoa, and their functional properties decrease. The spermatogenesis is a difficult, extremely sensible process of cellular differentiation; the different systems of organism participate in its adjusting. Violations in any links affect the process of spermatogenesis, and finally, affects parameters of semen. This systematic review of the literature analyses recent publications concerning studies of oxidative stress influencing male fertility. The oxidative stress - the very widespread version of pathology, which accompanies and/or is one of key mechanisms in development of many types of reproductive disorders in men. There are three main mechanisms of impaired fertile function of men in the development of oxidative stress: reducing sperm motility, violation of ability of spermatozoa to penetrate into oocyte and spermatozoa DNA damage. The factors promoting its development are numerous: environmental pollution, life style, addictions, stress, diabetes, and varicocele; however, the most frequent reason of development of oxidative stress in reproductive system of men are infectious and inflammatory diseases and antispermal autoimmune processes in a man's urogenital tract. Considering possible participation of free-radical processes in patospermia development, it is worthwhile to use antioxidants in all cases of the man's infertility connected with oxidative stress.E. A. KirilenkoV. F. OnopkoScientific Сentre for Family Health and Human Reproduction Problemsarticleoxidative stressreactive oxygen speciesmale infertilityantioxidantScienceQRUActa Biomedica Scientifica, Vol 2, Iss 2, Pp 102-108 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	oxidative stress reactive oxygen species male infertility antioxidant Science Q
spellingShingle	oxidative stress reactive oxygen species male infertility antioxidant Science Q E. A. Kirilenko V. F. Onopko OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM
description	Presently, the expressed tendency to deterioration in parameters of semen is noted in the world, at the same time both the quantity of spermatozoa, and their functional properties decrease. The spermatogenesis is a difficult, extremely sensible process of cellular differentiation; the different systems of organism participate in its adjusting. Violations in any links affect the process of spermatogenesis, and finally, affects parameters of semen. This systematic review of the literature analyses recent publications concerning studies of oxidative stress influencing male fertility. The oxidative stress - the very widespread version of pathology, which accompanies and/or is one of key mechanisms in development of many types of reproductive disorders in men. There are three main mechanisms of impaired fertile function of men in the development of oxidative stress: reducing sperm motility, violation of ability of spermatozoa to penetrate into oocyte and spermatozoa DNA damage. The factors promoting its development are numerous: environmental pollution, life style, addictions, stress, diabetes, and varicocele; however, the most frequent reason of development of oxidative stress in reproductive system of men are infectious and inflammatory diseases and antispermal autoimmune processes in a man's urogenital tract. Considering possible participation of free-radical processes in patospermia development, it is worthwhile to use antioxidants in all cases of the man's infertility connected with oxidative stress.
format	article
author	E. A. Kirilenko V. F. Onopko
author_facet	E. A. Kirilenko V. F. Onopko
author_sort	E. A. Kirilenko
title	OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM
title_short	OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM
title_full	OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM
title_fullStr	OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM
title_full_unstemmed	OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM
title_sort	oxidative stress and male fertility: modern view on the problem
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/b9e7d0867d244706952add2a20d88dc0
work_keys_str_mv	AT eakirilenko oxidativestressandmalefertilitymodernviewontheproblem AT vfonopko oxidativestressandmalefertilitymodernviewontheproblem
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OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM

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