Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study.

Electrophysiological studies of the human heart face the fundamental challenge that experimental data can be acquired only from patients with underlying heart disease. Regarding human atria, there exist sizable gaps in the understanding of the functional role of cellular Ca²+ dynamics, which differ...

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Bibliographic Details
Main Authors: Jussi T Koivumäki, Topi Korhonen, Pasi Tavi
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
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Online Access:https://doaj.org/article/b9ea382be02c455d9c27cdf917a402bf
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