Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study

This study aims to identify the association between the concentration of particulate matter <2.5 μm (PM2.5), <10 μm (PM10), and ozone (O3) and frailty. The Korean Frailty Scale (KFS, 0–6 points) assessing physical, psychologi...

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Autores principales:	Jinyoung Shin, Jaekyung Choi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	frail elderly air pollution particulate matter ozone Medicine R
Acceso en línea:	https://doaj.org/article/b9ef035743404dea86aa4df1299d6bf7
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spelling	oai:doaj.org-article:b9ef035743404dea86aa4df1299d6bf72021-11-25T17:48:30ZFrailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study10.3390/ijerph1822117961660-46011661-7827https://doaj.org/article/b9ef035743404dea86aa4df1299d6bf72021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/11796https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601This study aims to identify the association between the concentration of particulate matter <2.5 μm (PM<sub>2.5</sub>), <10 μm (PM<sub>10</sub>), and ozone (O<sub>3</sub>) and frailty. The Korean Frailty Scale (KFS, 0–6 points) assessing physical, psychological, and social frailty, was applied to 2912 community-dwelling older adults between April 2016 and December 2017. Daily average concentrations of PM<sub>2.5</sub>, PM<sub>10</sub>, and O<sub>3</sub> (2015–2017) were obtained and matched with the residential areas. The frailty risk associated with exposure to PM<sub>2.5</sub>, PM<sub>10</sub>, and O<sub>3</sub> was evaluated using multiple logistic regression after adjusting for age, sex, BMI, lifestyle, socioeconomic status, and comorbidity. Participants were categorized into robust (0 points, 28.7%), pre-frail (1–2 points, 50.1%), and frail (≥3 points, 21.2%) groups. Each 1 μg/m<sup>3</sup> increase of PM<sub>2.5</sub> and PM<sub>10</sub> increased the odds ratios (ORs) and 95% confidence intervals (CIs) of the frail group compared to the robust group: 1.055 (1.002, 1.112) and 1.095 (1.060, 1.131), and the pre-frail group: 1.053 (1.017, 1.090) and 1.062 (1.037, 1.087), respectively. Each 1-ppb increase of O<sub>3</sub> increased the OR (95% CI) of the frail group: 1.041 (1.023, 1.059) and the pre-frail group: 1.005 (0.985, 1.025). PM<sub>2.5</sub>, PM<sub>10</sub>, and O<sub>3</sub> may be associated dose-dependently with the frailty.Jinyoung ShinJaekyung ChoiMDPI AGarticlefrail elderlyair pollutionparticulate matterozoneMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11796, p 11796 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	frail elderly air pollution particulate matter ozone Medicine R
spellingShingle	frail elderly air pollution particulate matter ozone Medicine R Jinyoung Shin Jaekyung Choi Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study
description	This study aims to identify the association between the concentration of particulate matter <2.5 μm (PM<sub>2.5</sub>), <10 μm (PM<sub>10</sub>), and ozone (O<sub>3</sub>) and frailty. The Korean Frailty Scale (KFS, 0–6 points) assessing physical, psychological, and social frailty, was applied to 2912 community-dwelling older adults between April 2016 and December 2017. Daily average concentrations of PM<sub>2.5</sub>, PM<sub>10</sub>, and O<sub>3</sub> (2015–2017) were obtained and matched with the residential areas. The frailty risk associated with exposure to PM<sub>2.5</sub>, PM<sub>10</sub>, and O<sub>3</sub> was evaluated using multiple logistic regression after adjusting for age, sex, BMI, lifestyle, socioeconomic status, and comorbidity. Participants were categorized into robust (0 points, 28.7%), pre-frail (1–2 points, 50.1%), and frail (≥3 points, 21.2%) groups. Each 1 μg/m<sup>3</sup> increase of PM<sub>2.5</sub> and PM<sub>10</sub> increased the odds ratios (ORs) and 95% confidence intervals (CIs) of the frail group compared to the robust group: 1.055 (1.002, 1.112) and 1.095 (1.060, 1.131), and the pre-frail group: 1.053 (1.017, 1.090) and 1.062 (1.037, 1.087), respectively. Each 1-ppb increase of O<sub>3</sub> increased the OR (95% CI) of the frail group: 1.041 (1.023, 1.059) and the pre-frail group: 1.005 (0.985, 1.025). PM<sub>2.5</sub>, PM<sub>10</sub>, and O<sub>3</sub> may be associated dose-dependently with the frailty.
format	article
author	Jinyoung Shin Jaekyung Choi
author_facet	Jinyoung Shin Jaekyung Choi
author_sort	Jinyoung Shin
title	Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study
title_short	Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study
title_full	Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study
title_fullStr	Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study
title_full_unstemmed	Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study
title_sort	frailty related to the exposure to particulate matter and ozone: the korean frailty and aging cohort study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b9ef035743404dea86aa4df1299d6bf7
work_keys_str_mv	AT jinyoungshin frailtyrelatedtotheexposuretoparticulatematterandozonethekoreanfrailtyandagingcohortstudy AT jaekyungchoi frailtyrelatedtotheexposuretoparticulatematterandozonethekoreanfrailtyandagingcohortstudy
_version_	1718412007943700480

Frailty Related to the Exposure to Particulate Matter and Ozone: The Korean Frailty and Aging Cohort Study

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