Genome wide association analysis in a mouse advanced intercross line

Multigenerational outbred populations from an advanced intercross line (AIL) of mice represent useful resources for genome wide association analysis. Here, the authors analyze 1,063 LG x SM AIL mice to identify significant associations for 50 traits relevant to human health and disease.

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Autores principales: Natalia M. Gonzales, Jungkyun Seo, Ana I. Hernandez Cordero, Celine L. St. Pierre, Jennifer S. Gregory, Margaret G. Distler, Mark Abney, Stefan Canzar, Arimantas Lionikas, Abraham A. Palmer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b9f3f59ed9014b36ad09966559d40fb1
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spelling oai:doaj.org-article:b9f3f59ed9014b36ad09966559d40fb12021-12-02T14:41:07ZGenome wide association analysis in a mouse advanced intercross line10.1038/s41467-018-07642-82041-1723https://doaj.org/article/b9f3f59ed9014b36ad09966559d40fb12018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07642-8https://doaj.org/toc/2041-1723Multigenerational outbred populations from an advanced intercross line (AIL) of mice represent useful resources for genome wide association analysis. Here, the authors analyze 1,063 LG x SM AIL mice to identify significant associations for 50 traits relevant to human health and disease.Natalia M. GonzalesJungkyun SeoAna I. Hernandez CorderoCeline L. St. PierreJennifer S. GregoryMargaret G. DistlerMark AbneyStefan CanzarArimantas LionikasAbraham A. PalmerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Natalia M. Gonzales
Jungkyun Seo
Ana I. Hernandez Cordero
Celine L. St. Pierre
Jennifer S. Gregory
Margaret G. Distler
Mark Abney
Stefan Canzar
Arimantas Lionikas
Abraham A. Palmer
Genome wide association analysis in a mouse advanced intercross line
description Multigenerational outbred populations from an advanced intercross line (AIL) of mice represent useful resources for genome wide association analysis. Here, the authors analyze 1,063 LG x SM AIL mice to identify significant associations for 50 traits relevant to human health and disease.
format article
author Natalia M. Gonzales
Jungkyun Seo
Ana I. Hernandez Cordero
Celine L. St. Pierre
Jennifer S. Gregory
Margaret G. Distler
Mark Abney
Stefan Canzar
Arimantas Lionikas
Abraham A. Palmer
author_facet Natalia M. Gonzales
Jungkyun Seo
Ana I. Hernandez Cordero
Celine L. St. Pierre
Jennifer S. Gregory
Margaret G. Distler
Mark Abney
Stefan Canzar
Arimantas Lionikas
Abraham A. Palmer
author_sort Natalia M. Gonzales
title Genome wide association analysis in a mouse advanced intercross line
title_short Genome wide association analysis in a mouse advanced intercross line
title_full Genome wide association analysis in a mouse advanced intercross line
title_fullStr Genome wide association analysis in a mouse advanced intercross line
title_full_unstemmed Genome wide association analysis in a mouse advanced intercross line
title_sort genome wide association analysis in a mouse advanced intercross line
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/b9f3f59ed9014b36ad09966559d40fb1
work_keys_str_mv AT nataliamgonzales genomewideassociationanalysisinamouseadvancedintercrossline
AT jungkyunseo genomewideassociationanalysisinamouseadvancedintercrossline
AT anaihernandezcordero genomewideassociationanalysisinamouseadvancedintercrossline
AT celinelstpierre genomewideassociationanalysisinamouseadvancedintercrossline
AT jennifersgregory genomewideassociationanalysisinamouseadvancedintercrossline
AT margaretgdistler genomewideassociationanalysisinamouseadvancedintercrossline
AT markabney genomewideassociationanalysisinamouseadvancedintercrossline
AT stefancanzar genomewideassociationanalysisinamouseadvancedintercrossline
AT arimantaslionikas genomewideassociationanalysisinamouseadvancedintercrossline
AT abrahamapalmer genomewideassociationanalysisinamouseadvancedintercrossline
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