Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects.

Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects.

<h4>Background</h4>Previous studies identified melatonin receptor 1B (MTNR1B), islet-specific glucose 6 phosphatase catalytic subunit-related protein (G6PC2), glucokinase (GCK) and glucokinase regulatory protein (GCKR) as candidate genes for type 2 diabetes (T2D) acting through elevated...

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Main Authors: Claudia Ha Ting Tam, Janice Sin Ka Ho, Ying Wang, Heung Man Lee, Vincent Kwok Lim Lam, Soren Germer, Mitchell Martin, Wing Yee So, Ronald Ching Wan Ma, Juliana Chung Ngor Chan, Maggie Chor Yin Ng
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b9fae586310a4eb090493d47f4a01baf
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https://doaj.org/article/b9fae586310a4eb090493d47f4a01baf

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