Rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.

Reward probability and uncertainty are two fundamental parameters of decision making. Whereas reward probability indicates the prospect of winning, reward uncertainty, measured as the variance of probability, indicates the degree of risk. Several lines of evidence have suggested that the anterior ci...

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Autores principales: Rongjun Yu, Wu Zhou, Xiaolin Zhou
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Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/b9fbc99da744456babd45fb5b7ec5acf
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spelling oai:doaj.org-article:b9fbc99da744456babd45fb5b7ec5acf2021-11-18T07:31:29ZRapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.1932-620310.1371/journal.pone.0029633https://doaj.org/article/b9fbc99da744456babd45fb5b7ec5acf2011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22216335/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Reward probability and uncertainty are two fundamental parameters of decision making. Whereas reward probability indicates the prospect of winning, reward uncertainty, measured as the variance of probability, indicates the degree of risk. Several lines of evidence have suggested that the anterior cingulate cortex (ACC) plays an important role in reward processing. What is lacking is a quantitative analysis of the encoding of reward probability and uncertainty in the human ACC. In this study, we addressed this issue by analyzing the feedback-related negativity (FRN), an event-related potential (ERP) component that reflects the ACC activity, in a simple gambling task in which reward probability and uncertainty were parametrically manipulated through predicting cues. Results showed that at the outcome evaluation phase, while both win and loss-related FRN amplitudes increased as the probability of win or loss decreased, only the win-related FRN was modulated by reward uncertainty. This study demonstrates the rapid encoding of reward probability and uncertainty in the human ACC and offers new insights into the functions of the ACC.Rongjun YuWu ZhouXiaolin ZhouPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 12, p e29633 (2011)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Rongjun Yu
Wu Zhou
Xiaolin Zhou
Rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.
description Reward probability and uncertainty are two fundamental parameters of decision making. Whereas reward probability indicates the prospect of winning, reward uncertainty, measured as the variance of probability, indicates the degree of risk. Several lines of evidence have suggested that the anterior cingulate cortex (ACC) plays an important role in reward processing. What is lacking is a quantitative analysis of the encoding of reward probability and uncertainty in the human ACC. In this study, we addressed this issue by analyzing the feedback-related negativity (FRN), an event-related potential (ERP) component that reflects the ACC activity, in a simple gambling task in which reward probability and uncertainty were parametrically manipulated through predicting cues. Results showed that at the outcome evaluation phase, while both win and loss-related FRN amplitudes increased as the probability of win or loss decreased, only the win-related FRN was modulated by reward uncertainty. This study demonstrates the rapid encoding of reward probability and uncertainty in the human ACC and offers new insights into the functions of the ACC.
format article
author Rongjun Yu
Wu Zhou
Xiaolin Zhou
author_facet Rongjun Yu
Wu Zhou
Xiaolin Zhou
author_sort Rongjun Yu
title Rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.
title_short Rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.
title_full Rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.
title_fullStr Rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.
title_full_unstemmed Rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.
title_sort rapid processing of both reward probability and reward uncertainty in the human anterior cingulate cortex.
publisher Public Library of Science (PLoS)
publishDate 2011
url https://doaj.org/article/b9fbc99da744456babd45fb5b7ec5acf
work_keys_str_mv AT rongjunyu rapidprocessingofbothrewardprobabilityandrewarduncertaintyinthehumananteriorcingulatecortex
AT wuzhou rapidprocessingofbothrewardprobabilityandrewarduncertaintyinthehumananteriorcingulatecortex
AT xiaolinzhou rapidprocessingofbothrewardprobabilityandrewarduncertaintyinthehumananteriorcingulatecortex
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