Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder

Background: We evaluated the feasibility and safety of stentless uretero-intestinal anastomosis (UIA) during radical cystectomy (RC) with an ileal orthotopic neobladder. Methods: We retrospectively reviewed 403 patients who underwent RC for bladder cancer between August 2014 and December 2018. The p...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Chung Un Lee, Jong Hoon Lee, Dong Hyeon Lee, Wan Song
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	complications neobladder radical cystectomy stentless uretero-intestinal anastomosis Medicine R
Acceso en línea:	https://doaj.org/article/b9fc400d7dc8401ba42a621d4a3dcbee
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b9fc400d7dc8401ba42a621d4a3dcbee
record_format	dspace
spelling	oai:doaj.org-article:b9fc400d7dc8401ba42a621d4a3dcbee2021-11-25T18:02:12ZFeasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder10.3390/jcm102253722077-0383https://doaj.org/article/b9fc400d7dc8401ba42a621d4a3dcbee2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5372https://doaj.org/toc/2077-0383Background: We evaluated the feasibility and safety of stentless uretero-intestinal anastomosis (UIA) during radical cystectomy (RC) with an ileal orthotopic neobladder. Methods: We retrospectively reviewed 403 patients who underwent RC for bladder cancer between August 2014 and December 2018. The primary objective was to study the effect of stentless UIA on uretero-intestinal anastomosis stricture (UIAS), and the secondary objective was to evaluate the association between stentless UIA and other complications, including paralytic ileus, febrile urinary tract infection (UTI), and urine leakage. Kaplan–Meier survival analysis was used to estimate UIAS-free survival, and Cox proportional hazard models were applied to identify factors associated with the risk of UIAS. Results: Among 403 patients with 790 renal units, UIAS was identified in 39 (9.7%) patients and 53 (6.7%) renal units. Forty-four (83.0%) patients with UIAS were diagnosed within 6 months. The 1- and 2-year overall UIAS-free rates were 93.9% and 92.7%, respectively. Paralytic ileus was identified in 105 (26.1%) patients and resolved with supportive treatment. Febrile UTI occurred in 57 patients (14.1%). However, there was no leak of the UIA. Conclusions: Stentless UIA during RC with an ileal orthotopic neobladder is a feasible and safe surgical option. Further prospective randomized trials are required to determine the clinical usefulness of stentless UIA during RC.Chung Un LeeJong Hoon LeeDong Hyeon LeeWan SongMDPI AGarticlecomplicationsneobladderradical cystectomystentlessuretero-intestinal anastomosisMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5372, p 5372 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	complications neobladder radical cystectomy stentless uretero-intestinal anastomosis Medicine R
spellingShingle	complications neobladder radical cystectomy stentless uretero-intestinal anastomosis Medicine R Chung Un Lee Jong Hoon Lee Dong Hyeon Lee Wan Song Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder
description	Background: We evaluated the feasibility and safety of stentless uretero-intestinal anastomosis (UIA) during radical cystectomy (RC) with an ileal orthotopic neobladder. Methods: We retrospectively reviewed 403 patients who underwent RC for bladder cancer between August 2014 and December 2018. The primary objective was to study the effect of stentless UIA on uretero-intestinal anastomosis stricture (UIAS), and the secondary objective was to evaluate the association between stentless UIA and other complications, including paralytic ileus, febrile urinary tract infection (UTI), and urine leakage. Kaplan–Meier survival analysis was used to estimate UIAS-free survival, and Cox proportional hazard models were applied to identify factors associated with the risk of UIAS. Results: Among 403 patients with 790 renal units, UIAS was identified in 39 (9.7%) patients and 53 (6.7%) renal units. Forty-four (83.0%) patients with UIAS were diagnosed within 6 months. The 1- and 2-year overall UIAS-free rates were 93.9% and 92.7%, respectively. Paralytic ileus was identified in 105 (26.1%) patients and resolved with supportive treatment. Febrile UTI occurred in 57 patients (14.1%). However, there was no leak of the UIA. Conclusions: Stentless UIA during RC with an ileal orthotopic neobladder is a feasible and safe surgical option. Further prospective randomized trials are required to determine the clinical usefulness of stentless UIA during RC.
format	article
author	Chung Un Lee Jong Hoon Lee Dong Hyeon Lee Wan Song
author_facet	Chung Un Lee Jong Hoon Lee Dong Hyeon Lee Wan Song
author_sort	Chung Un Lee
title	Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder
title_short	Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder
title_full	Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder
title_fullStr	Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder
title_full_unstemmed	Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder
title_sort	feasibility and safety of stentless uretero-intestinal anastomosis in radical cystectomy with ileal orthotopic neobladder
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b9fc400d7dc8401ba42a621d4a3dcbee
work_keys_str_mv	AT chungunlee feasibilityandsafetyofstentlessureterointestinalanastomosisinradicalcystectomywithilealorthotopicneobladder AT jonghoonlee feasibilityandsafetyofstentlessureterointestinalanastomosisinradicalcystectomywithilealorthotopicneobladder AT donghyeonlee feasibilityandsafetyofstentlessureterointestinalanastomosisinradicalcystectomywithilealorthotopicneobladder AT wansong feasibilityandsafetyofstentlessureterointestinalanastomosisinradicalcystectomywithilealorthotopicneobladder
_version_	1718411704153407488

Feasibility and Safety of Stentless Uretero-Intestinal Anastomosis in Radical Cystectomy with Ileal Orthotopic Neobladder

Ejemplares similares