Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125

The efficacy of diet and its influence on gut microbiome composition has been largely demonstrated in inflammatory bowel disease (IBD). Little is known about its potential in the management of extraintestinal manifestations. We report a successful application of Crohn disease exclusion diet (CDED) i...

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Autores principales:	Erika Cantarelli, Francesco Baccelli, Gabriele Simonini, Patrizia Alvisi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	resistant Crohn disease chronic recurrent multifocal osteomyelitis Crohn disease exclusion diet Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/b9fe7430545a4105b6160cd2b6646632
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spelling	oai:doaj.org-article:b9fe7430545a4105b6160cd2b66466322021-11-25T18:36:00ZChronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 212510.3390/nu131140052072-6643https://doaj.org/article/b9fe7430545a4105b6160cd2b66466322021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4005https://doaj.org/toc/2072-6643The efficacy of diet and its influence on gut microbiome composition has been largely demonstrated in inflammatory bowel disease (IBD). Little is known about its potential in the management of extraintestinal manifestations. We report a successful application of Crohn disease exclusion diet (CDED) in association with infliximab and methotrexate, as salvage therapy in a child affected by chronic recurrent multifocal osteomyelitis (CRMO) and Crohn disease (CD) resistant to optimized therapy. Both intestinal and bone symptoms remitted after the application of CDED. Diet may have acted on common microbic inciting agents that trigger both intestinal and bone inflammation, supporting the role of microbiota in the pathogenesis of IBD-associated extraintestinal manifestations. Our experience suggests the potential benefit of CDED in association with combined therapy in resistant patients affected by CD and extraintestinal manifestations.Erika CantarelliFrancesco BaccelliGabriele SimoniniPatrizia AlvisiMDPI AGarticleresistant Crohn diseasechronic recurrent multifocal osteomyelitisCrohn disease exclusion dietNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4005, p 4005 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	resistant Crohn disease chronic recurrent multifocal osteomyelitis Crohn disease exclusion diet Nutrition. Foods and food supply TX341-641
spellingShingle	resistant Crohn disease chronic recurrent multifocal osteomyelitis Crohn disease exclusion diet Nutrition. Foods and food supply TX341-641 Erika Cantarelli Francesco Baccelli Gabriele Simonini Patrizia Alvisi Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125
description	The efficacy of diet and its influence on gut microbiome composition has been largely demonstrated in inflammatory bowel disease (IBD). Little is known about its potential in the management of extraintestinal manifestations. We report a successful application of Crohn disease exclusion diet (CDED) in association with infliximab and methotrexate, as salvage therapy in a child affected by chronic recurrent multifocal osteomyelitis (CRMO) and Crohn disease (CD) resistant to optimized therapy. Both intestinal and bone symptoms remitted after the application of CDED. Diet may have acted on common microbic inciting agents that trigger both intestinal and bone inflammation, supporting the role of microbiota in the pathogenesis of IBD-associated extraintestinal manifestations. Our experience suggests the potential benefit of CDED in association with combined therapy in resistant patients affected by CD and extraintestinal manifestations.
format	article
author	Erika Cantarelli Francesco Baccelli Gabriele Simonini Patrizia Alvisi
author_facet	Erika Cantarelli Francesco Baccelli Gabriele Simonini Patrizia Alvisi
author_sort	Erika Cantarelli
title	Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125
title_short	Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125
title_full	Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125
title_fullStr	Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125
title_full_unstemmed	Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125
title_sort	chronic recurrent multifocal osteomyelitis associated with crohn disease: a potential role of exclusion diet? comment on starz et al. the modification of the gut microbiota via selected specific diets in patients with crohn’s disease. <i>nutrients</i> 2021, <i>13</i>, 2125
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b9fe7430545a4105b6160cd2b6646632
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Chronic Recurrent Multifocal Osteomyelitis Associated with Crohn Disease: A Potential Role of Exclusion Diet? Comment on Starz et al. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. <i>Nutrients</i> 2021, <i>13</i>, 2125

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