A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia

A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia

The number of tRNA isodecoders has expanded significantly during evolution, which has resulted in ambiguity in tRNA selection by synthetases. Here the authors identify and characterize a dedicated proofreading factor that eliminates errors caused by ambiguity in tRNA selection by eukaryotic tRNA syn...

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Autores principales: Santosh Kumar Kuncha, Mohd Mazeed, Raghvendra Singh, Bhavita Kattula, Satya Brata Routh, Rajan Sankaranarayanan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b9ffb78b9dda4f2c91cc1835bdec3b7f
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spelling oai:doaj.org-article:b9ffb78b9dda4f2c91cc1835bdec3b7f2021-12-02T17:33:18ZA chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia10.1038/s41467-017-02204-w2041-1723https://doaj.org/article/b9ffb78b9dda4f2c91cc1835bdec3b7f2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02204-whttps://doaj.org/toc/2041-1723The number of tRNA isodecoders has expanded significantly during evolution, which has resulted in ambiguity in tRNA selection by synthetases. Here the authors identify and characterize a dedicated proofreading factor that eliminates errors caused by ambiguity in tRNA selection by eukaryotic tRNA synthetases.Santosh Kumar KunchaMohd MazeedRaghvendra SinghBhavita KattulaSatya Brata RouthRajan SankaranarayananNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Santosh Kumar Kuncha
Mohd Mazeed
Raghvendra Singh
Bhavita Kattula
Satya Brata Routh
Rajan Sankaranarayanan
A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
description The number of tRNA isodecoders has expanded significantly during evolution, which has resulted in ambiguity in tRNA selection by synthetases. Here the authors identify and characterize a dedicated proofreading factor that eliminates errors caused by ambiguity in tRNA selection by eukaryotic tRNA synthetases.
format article
author Santosh Kumar Kuncha
Mohd Mazeed
Raghvendra Singh
Bhavita Kattula
Satya Brata Routh
Rajan Sankaranarayanan
author_facet Santosh Kumar Kuncha
Mohd Mazeed
Raghvendra Singh
Bhavita Kattula
Satya Brata Routh
Rajan Sankaranarayanan
author_sort Santosh Kumar Kuncha
title A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
title_short A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
title_full A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
title_fullStr A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
title_full_unstemmed A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
title_sort chiral selectivity relaxed paralog of dtd for proofreading trna mischarging in animalia
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/b9ffb78b9dda4f2c91cc1835bdec3b7f
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