Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair

Sarcolemma lesions are sealed by a repair patch of lipids and proteins that prevents cell death and myopathy. Here the authors show that the "eat-me" signal phosphatidylserine is sorted from adjacent sarcolemma to the repair patch in a Dysferlin dependent process in zebrafish and human cel...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Volker Middel, Lu Zhou, Masanari Takamiya, Tanja Beil, Maryam Shahid, Urmas Roostalu, Clemens Grabher, Sepand Rastegar, Markus Reischl, Gerd Ulrich Nienhaus, Uwe Strähle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ba0b4d8e1f2f4b2dac680e4b682a365b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ba0b4d8e1f2f4b2dac680e4b682a365b
record_format	dspace
spelling	oai:doaj.org-article:ba0b4d8e1f2f4b2dac680e4b682a365b2021-12-02T16:57:05ZDysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair10.1038/ncomms128752041-1723https://doaj.org/article/ba0b4d8e1f2f4b2dac680e4b682a365b2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12875https://doaj.org/toc/2041-1723Sarcolemma lesions are sealed by a repair patch of lipids and proteins that prevents cell death and myopathy. Here the authors show that the "eat-me" signal phosphatidylserine is sorted from adjacent sarcolemma to the repair patch in a Dysferlin dependent process in zebrafish and human cells.Volker MiddelLu ZhouMasanari TakamiyaTanja BeilMaryam ShahidUrmas RoostaluClemens GrabherSepand RastegarMarkus ReischlGerd Ulrich NienhausUwe SträhleNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Volker Middel Lu Zhou Masanari Takamiya Tanja Beil Maryam Shahid Urmas Roostalu Clemens Grabher Sepand Rastegar Markus Reischl Gerd Ulrich Nienhaus Uwe Strähle Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
description	Sarcolemma lesions are sealed by a repair patch of lipids and proteins that prevents cell death and myopathy. Here the authors show that the "eat-me" signal phosphatidylserine is sorted from adjacent sarcolemma to the repair patch in a Dysferlin dependent process in zebrafish and human cells.
format	article
author	Volker Middel Lu Zhou Masanari Takamiya Tanja Beil Maryam Shahid Urmas Roostalu Clemens Grabher Sepand Rastegar Markus Reischl Gerd Ulrich Nienhaus Uwe Strähle
author_facet	Volker Middel Lu Zhou Masanari Takamiya Tanja Beil Maryam Shahid Urmas Roostalu Clemens Grabher Sepand Rastegar Markus Reischl Gerd Ulrich Nienhaus Uwe Strähle
author_sort	Volker Middel
title	Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
title_short	Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
title_full	Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
title_fullStr	Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
title_full_unstemmed	Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
title_sort	dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/ba0b4d8e1f2f4b2dac680e4b682a365b
work_keys_str_mv	AT volkermiddel dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT luzhou dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT masanaritakamiya dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT tanjabeil dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT maryamshahid dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT urmasroostalu dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT clemensgrabher dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT sepandrastegar dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT markusreischl dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT gerdulrichnienhaus dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair AT uwestrahle dysferlinmediatedphosphatidylserinesortingengagesmacrophagesinsarcolemmarepair
_version_	1718382644215939072

Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair

Ejemplares similares