Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes

More than 100 risk loci for schizophrenia have been identified by genome-wide association studies. Here, the authors apply an integrative genomic approach to prioritize risk genes and validate GLT8D1 and CSNK2B as candidate causal genes by in vitro studies in neural stem cells.

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Autores principales:	Cui-Ping Yang, Xiaoyan Li, Yong Wu, Qiushuo Shen, Yong Zeng, Qiuxia Xiong, Mengping Wei, Chunhui Chen, Jiewei Liu, Yongxia Huo, Kaiqin Li, Gui Xue, Yong-Gang Yao, Chen Zhang, Ming Li, Yongbin Chen, Xiong-Jian Luo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ba12e6b9e8a940f9954895f9f71b1408
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spelling	oai:doaj.org-article:ba12e6b9e8a940f9954895f9f71b14082021-12-02T15:34:45ZComprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes10.1038/s41467-018-03247-32041-1723https://doaj.org/article/ba12e6b9e8a940f9954895f9f71b14082018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03247-3https://doaj.org/toc/2041-1723More than 100 risk loci for schizophrenia have been identified by genome-wide association studies. Here, the authors apply an integrative genomic approach to prioritize risk genes and validate GLT8D1 and CSNK2B as candidate causal genes by in vitro studies in neural stem cells.Cui-Ping YangXiaoyan LiYong WuQiushuo ShenYong ZengQiuxia XiongMengping WeiChunhui ChenJiewei LiuYongxia HuoKaiqin LiGui XueYong-Gang YaoChen ZhangMing LiYongbin ChenXiong-Jian LuoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cui-Ping Yang Xiaoyan Li Yong Wu Qiushuo Shen Yong Zeng Qiuxia Xiong Mengping Wei Chunhui Chen Jiewei Liu Yongxia Huo Kaiqin Li Gui Xue Yong-Gang Yao Chen Zhang Ming Li Yongbin Chen Xiong-Jian Luo Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
description	More than 100 risk loci for schizophrenia have been identified by genome-wide association studies. Here, the authors apply an integrative genomic approach to prioritize risk genes and validate GLT8D1 and CSNK2B as candidate causal genes by in vitro studies in neural stem cells.
format	article
author	Cui-Ping Yang Xiaoyan Li Yong Wu Qiushuo Shen Yong Zeng Qiuxia Xiong Mengping Wei Chunhui Chen Jiewei Liu Yongxia Huo Kaiqin Li Gui Xue Yong-Gang Yao Chen Zhang Ming Li Yongbin Chen Xiong-Jian Luo
author_facet	Cui-Ping Yang Xiaoyan Li Yong Wu Qiushuo Shen Yong Zeng Qiuxia Xiong Mengping Wei Chunhui Chen Jiewei Liu Yongxia Huo Kaiqin Li Gui Xue Yong-Gang Yao Chen Zhang Ming Li Yongbin Chen Xiong-Jian Luo
author_sort	Cui-Ping Yang
title	Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
title_short	Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
title_full	Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
title_fullStr	Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
title_full_unstemmed	Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
title_sort	comprehensive integrative analyses identify glt8d1 and csnk2b as schizophrenia risk genes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ba12e6b9e8a940f9954895f9f71b1408
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Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes

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