Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver

Few studies have provided functional analysis of the epigenetic landscape in the regenerating liver. Here the authors define chromatin states in the quiescent vs. regenerating mouse liver through integration of genome wide profiles of DNA methylation, histone modifications, and chromatin accessibili...

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Autores principales:	Chi Zhang, Filippo Macchi, Elena Magnani, Kirsten C. Sadler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ba1340026bc242589db44cb89dff29c9
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spelling	oai:doaj.org-article:ba1340026bc242589db44cb89dff29c92021-12-02T15:23:19ZChromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver10.1038/s41467-021-24466-12041-1723https://doaj.org/article/ba1340026bc242589db44cb89dff29c92021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24466-1https://doaj.org/toc/2041-1723Few studies have provided functional analysis of the epigenetic landscape in the regenerating liver. Here the authors define chromatin states in the quiescent vs. regenerating mouse liver through integration of genome wide profiles of DNA methylation, histone modifications, and chromatin accessibility, identifying H3K27me3 as an epigenetic mark conferring regenerative potential.Chi ZhangFilippo MacchiElena MagnaniKirsten C. SadlerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chi Zhang Filippo Macchi Elena Magnani Kirsten C. Sadler Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
description	Few studies have provided functional analysis of the epigenetic landscape in the regenerating liver. Here the authors define chromatin states in the quiescent vs. regenerating mouse liver through integration of genome wide profiles of DNA methylation, histone modifications, and chromatin accessibility, identifying H3K27me3 as an epigenetic mark conferring regenerative potential.
format	article
author	Chi Zhang Filippo Macchi Elena Magnani Kirsten C. Sadler
author_facet	Chi Zhang Filippo Macchi Elena Magnani Kirsten C. Sadler
author_sort	Chi Zhang
title	Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
title_short	Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
title_full	Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
title_fullStr	Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
title_full_unstemmed	Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
title_sort	chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ba1340026bc242589db44cb89dff29c9
work_keys_str_mv	AT chizhang chromatinstatesshapedbyanepigeneticcodeconferregenerativepotentialtothemouseliver AT filippomacchi chromatinstatesshapedbyanepigeneticcodeconferregenerativepotentialtothemouseliver AT elenamagnani chromatinstatesshapedbyanepigeneticcodeconferregenerativepotentialtothemouseliver AT kirstencsadler chromatinstatesshapedbyanepigeneticcodeconferregenerativepotentialtothemouseliver
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Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liver

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