Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration
Abstract Mild blast traumatic brain injury (B-TBI) induced lasting cognitive impairments in novel object recognition and less severe deficits in Y-maze behaviors. B-TBI significantly reduced the levels of synaptophysin (SYP) protein staining in cortical (CTX) and hippocampal (HIPP) tissues. Treatmen...
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Auteurs principaux: | Lital Rachmany, David Tweedie, Vardit Rubovitch, Yazhou Li, Harold W. Holloway, Dong Seok Kim, Whitney A. Ratliff, Jessica N. Saykally, Bruce A. Citron, Barry J. Hoffer, Nigel H. Greig, Chaim G. Pick |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/ba14dd0658e44105ac602a7fca068d44 |
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