Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons

α-Synuclein aggregation contributes to Parkinson’s disease and related disorders. Here the authors investigate patterns of α-synuclein aggregation in human dopaminergic neurons in response to fibrils derived from individuals with Parkinson’s disease or multiple system atrophy.

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Autores principales:	Benedict Tanudjojo, Samiha S. Shaikh, Alexis Fenyi, Luc Bousset, Devika Agarwal, Jade Marsh, Christos Zois, Sabrina Heman-Ackah, Roman Fischer, David Sims, Ronald Melki, George K. Tofaris
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ba1ca4aa1df444ff85f3d901ea6d3c50
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spelling	oai:doaj.org-article:ba1ca4aa1df444ff85f3d901ea6d3c502021-12-02T16:06:03ZPhenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons10.1038/s41467-021-23682-z2041-1723https://doaj.org/article/ba1ca4aa1df444ff85f3d901ea6d3c502021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23682-zhttps://doaj.org/toc/2041-1723α-Synuclein aggregation contributes to Parkinson’s disease and related disorders. Here the authors investigate patterns of α-synuclein aggregation in human dopaminergic neurons in response to fibrils derived from individuals with Parkinson’s disease or multiple system atrophy.Benedict TanudjojoSamiha S. ShaikhAlexis FenyiLuc BoussetDevika AgarwalJade MarshChristos ZoisSabrina Heman-AckahRoman FischerDavid SimsRonald MelkiGeorge K. TofarisNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benedict Tanudjojo Samiha S. Shaikh Alexis Fenyi Luc Bousset Devika Agarwal Jade Marsh Christos Zois Sabrina Heman-Ackah Roman Fischer David Sims Ronald Melki George K. Tofaris Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
description	α-Synuclein aggregation contributes to Parkinson’s disease and related disorders. Here the authors investigate patterns of α-synuclein aggregation in human dopaminergic neurons in response to fibrils derived from individuals with Parkinson’s disease or multiple system atrophy.
format	article
author	Benedict Tanudjojo Samiha S. Shaikh Alexis Fenyi Luc Bousset Devika Agarwal Jade Marsh Christos Zois Sabrina Heman-Ackah Roman Fischer David Sims Ronald Melki George K. Tofaris
author_facet	Benedict Tanudjojo Samiha S. Shaikh Alexis Fenyi Luc Bousset Devika Agarwal Jade Marsh Christos Zois Sabrina Heman-Ackah Roman Fischer David Sims Ronald Melki George K. Tofaris
author_sort	Benedict Tanudjojo
title	Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
title_short	Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
title_full	Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
title_fullStr	Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
title_full_unstemmed	Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
title_sort	phenotypic manifestation of α-synuclein strains derived from parkinson’s disease and multiple system atrophy in human dopaminergic neurons
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ba1ca4aa1df444ff85f3d901ea6d3c50
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Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons

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