Cellular and synaptic phenotypes lead to disrupted information processing in Fmr1-KO mouse layer 4 barrel cortex

Somatosensory hypersensitivity in Fmr-1 knockout mice is thought to arise from an increase in cortical circuit excitability. Here, the authors report that the loss of precision of sensory encoding in the Layer 4 of barrel cortex is the primary developmental circuit alteration that drives the other c...

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Bibliographic Details
Main Authors: Aleksander P. F. Domanski, Sam A. Booker, David J. A. Wyllie, John T. R. Isaac, Peter C. Kind
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/ba220841587e4c75bd2141b3e2677e5b
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