Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

The white pulp of spleen is an important immune structure dynamically modulated during development and immune responses. Here the authors define, using multi-color lineage tracing and single-cell transcriptome analysis, the subset distribution and differentiation trajectory of fibroblastic reticular...

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Autores principales:	Hung-Wei Cheng, Lucas Onder, Mario Novkovic, Charlotte Soneson, Mechthild Lütge, Natalia Pikor, Elke Scandella, Mark D. Robinson, Jun-ichi Miyazaki, Anne Tersteegen, Ursula Sorg, Klaus Pfeffer, Thomas Rülicke, Thomas Hehlgans, Burkhard Ludewig
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ba256f3e23034aedb297741e8c98ad23
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spelling	oai:doaj.org-article:ba256f3e23034aedb297741e8c98ad232021-12-02T16:58:27ZOrigin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp10.1038/s41467-019-09728-32041-1723https://doaj.org/article/ba256f3e23034aedb297741e8c98ad232019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09728-3https://doaj.org/toc/2041-1723The white pulp of spleen is an important immune structure dynamically modulated during development and immune responses. Here the authors define, using multi-color lineage tracing and single-cell transcriptome analysis, the subset distribution and differentiation trajectory of fibroblastic reticular cells to serve structural insights for splenic white pulps.Hung-Wei ChengLucas OnderMario NovkovicCharlotte SonesonMechthild LütgeNatalia PikorElke ScandellaMark D. RobinsonJun-ichi MiyazakiAnne TersteegenUrsula SorgKlaus PfefferThomas RülickeThomas HehlgansBurkhard LudewigNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hung-Wei Cheng Lucas Onder Mario Novkovic Charlotte Soneson Mechthild Lütge Natalia Pikor Elke Scandella Mark D. Robinson Jun-ichi Miyazaki Anne Tersteegen Ursula Sorg Klaus Pfeffer Thomas Rülicke Thomas Hehlgans Burkhard Ludewig Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
description	The white pulp of spleen is an important immune structure dynamically modulated during development and immune responses. Here the authors define, using multi-color lineage tracing and single-cell transcriptome analysis, the subset distribution and differentiation trajectory of fibroblastic reticular cells to serve structural insights for splenic white pulps.
format	article
author	Hung-Wei Cheng Lucas Onder Mario Novkovic Charlotte Soneson Mechthild Lütge Natalia Pikor Elke Scandella Mark D. Robinson Jun-ichi Miyazaki Anne Tersteegen Ursula Sorg Klaus Pfeffer Thomas Rülicke Thomas Hehlgans Burkhard Ludewig
author_facet	Hung-Wei Cheng Lucas Onder Mario Novkovic Charlotte Soneson Mechthild Lütge Natalia Pikor Elke Scandella Mark D. Robinson Jun-ichi Miyazaki Anne Tersteegen Ursula Sorg Klaus Pfeffer Thomas Rülicke Thomas Hehlgans Burkhard Ludewig
author_sort	Hung-Wei Cheng
title	Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
title_short	Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
title_full	Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
title_fullStr	Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
title_full_unstemmed	Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
title_sort	origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ba256f3e23034aedb297741e8c98ad23
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_version_	1718382290258624512

Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

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