Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property

Abstract Nanopesticide is one of the best pesticide formulation technologies to overcome the disadvantages of traditional pesticides, which has received great attention from the international community. Using high-speed emulsification and ultrasonic dispersion technology, an avermectin nano-delivery...

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Autores principales:	Dongmei Mo, Xiangying Li, Yong Chen, Yang Jiang, Chunfang Gan, Yuanfei Zhang, Weiguo Li, Yanmin Huang, Jianguo Cui
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ba29ef088a864218acb9cc4c8820d345
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spelling	oai:doaj.org-article:ba29ef088a864218acb9cc4c8820d3452021-12-05T12:15:25ZFabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property10.1038/s41598-021-02664-72045-2322https://doaj.org/article/ba29ef088a864218acb9cc4c8820d3452021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02664-7https://doaj.org/toc/2045-2322Abstract Nanopesticide is one of the best pesticide formulation technologies to overcome the disadvantages of traditional pesticides, which has received great attention from the international community. Using high-speed emulsification and ultrasonic dispersion technology, an avermectin nano-delivery system (Av-NDs) with a particle size of 80–150 nm was prepared through embedding the pesticide molecule utilizing the cross-linking reaction between sodium lignosulfonate and p-phenylenediamine diazonium salt. The formulation and composition of Av-NDs were optimized, the morphology of Av-NDs was analyzed by scanning electron microscope, transmission electron microscope and dynamic light scattering, and the structure of Av-NDs was characterized by UV, IR and 1H NMR. Anti-photolysis and controlled-release tests show that the stability of Av-NDs is 3–4 times of the original avermectin (Av) and possesses the pH-responsive controlled release property. Furthermore, the insecticidal activity of Av-NDs is better than that of avermectin suspension concentrate (Av-SC). The Av-NDs with anti-photolysis and controlled-release characteristics is suitable for large-scale industrial production and is capable to be utilized as effective insecticide in the field.Dongmei MoXiangying LiYong ChenYang JiangChunfang GanYuanfei ZhangWeiguo LiYanmin HuangJianguo CuiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dongmei Mo Xiangying Li Yong Chen Yang Jiang Chunfang Gan Yuanfei Zhang Weiguo Li Yanmin Huang Jianguo Cui Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property
description	Abstract Nanopesticide is one of the best pesticide formulation technologies to overcome the disadvantages of traditional pesticides, which has received great attention from the international community. Using high-speed emulsification and ultrasonic dispersion technology, an avermectin nano-delivery system (Av-NDs) with a particle size of 80–150 nm was prepared through embedding the pesticide molecule utilizing the cross-linking reaction between sodium lignosulfonate and p-phenylenediamine diazonium salt. The formulation and composition of Av-NDs were optimized, the morphology of Av-NDs was analyzed by scanning electron microscope, transmission electron microscope and dynamic light scattering, and the structure of Av-NDs was characterized by UV, IR and 1H NMR. Anti-photolysis and controlled-release tests show that the stability of Av-NDs is 3–4 times of the original avermectin (Av) and possesses the pH-responsive controlled release property. Furthermore, the insecticidal activity of Av-NDs is better than that of avermectin suspension concentrate (Av-SC). The Av-NDs with anti-photolysis and controlled-release characteristics is suitable for large-scale industrial production and is capable to be utilized as effective insecticide in the field.
format	article
author	Dongmei Mo Xiangying Li Yong Chen Yang Jiang Chunfang Gan Yuanfei Zhang Weiguo Li Yanmin Huang Jianguo Cui
author_facet	Dongmei Mo Xiangying Li Yong Chen Yang Jiang Chunfang Gan Yuanfei Zhang Weiguo Li Yanmin Huang Jianguo Cui
author_sort	Dongmei Mo
title	Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property
title_short	Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property
title_full	Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property
title_fullStr	Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property
title_full_unstemmed	Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property
title_sort	fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with uv-shielding property
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ba29ef088a864218acb9cc4c8820d345
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Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property

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