Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection
Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.
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Nature Portfolio
2020
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oai:doaj.org-article:ba32f60be74545d6b1590448839902d62021-12-02T15:33:31ZTcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection10.1038/s41467-020-16219-32041-1723https://doaj.org/article/ba32f60be74545d6b1590448839902d62020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16219-3https://doaj.org/toc/2041-1723Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.Suzanne P. M. WeltenAlexander YermanosNicolas S. BaumannFranziska WagenNathalie OetikerIoana SanduAlessandro PedrioliJennifer D. OduroSai T. ReddyLuka Cicin-SainWerner HeldAnnette OxeniusNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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Science Q |
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Science Q Suzanne P. M. Welten Alexander Yermanos Nicolas S. Baumann Franziska Wagen Nathalie Oetiker Ioana Sandu Alessandro Pedrioli Jennifer D. Oduro Sai T. Reddy Luka Cicin-Sain Werner Held Annette Oxenius Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection |
description |
Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process. |
format |
article |
author |
Suzanne P. M. Welten Alexander Yermanos Nicolas S. Baumann Franziska Wagen Nathalie Oetiker Ioana Sandu Alessandro Pedrioli Jennifer D. Oduro Sai T. Reddy Luka Cicin-Sain Werner Held Annette Oxenius |
author_facet |
Suzanne P. M. Welten Alexander Yermanos Nicolas S. Baumann Franziska Wagen Nathalie Oetiker Ioana Sandu Alessandro Pedrioli Jennifer D. Oduro Sai T. Reddy Luka Cicin-Sain Werner Held Annette Oxenius |
author_sort |
Suzanne P. M. Welten |
title |
Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection |
title_short |
Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection |
title_full |
Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection |
title_fullStr |
Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection |
title_full_unstemmed |
Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection |
title_sort |
tcf1+ cells are required to maintain the inflationary t cell pool upon mcmv infection |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/ba32f60be74545d6b1590448839902d6 |
work_keys_str_mv |
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1718387103432179712 |