Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection

Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.

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Autores principales: Suzanne P. M. Welten, Alexander Yermanos, Nicolas S. Baumann, Franziska Wagen, Nathalie Oetiker, Ioana Sandu, Alessandro Pedrioli, Jennifer D. Oduro, Sai T. Reddy, Luka Cicin-Sain, Werner Held, Annette Oxenius
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ba32f60be74545d6b1590448839902d6
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spelling oai:doaj.org-article:ba32f60be74545d6b1590448839902d62021-12-02T15:33:31ZTcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection10.1038/s41467-020-16219-32041-1723https://doaj.org/article/ba32f60be74545d6b1590448839902d62020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16219-3https://doaj.org/toc/2041-1723Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.Suzanne P. M. WeltenAlexander YermanosNicolas S. BaumannFranziska WagenNathalie OetikerIoana SanduAlessandro PedrioliJennifer D. OduroSai T. ReddyLuka Cicin-SainWerner HeldAnnette OxeniusNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Suzanne P. M. Welten
Alexander Yermanos
Nicolas S. Baumann
Franziska Wagen
Nathalie Oetiker
Ioana Sandu
Alessandro Pedrioli
Jennifer D. Oduro
Sai T. Reddy
Luka Cicin-Sain
Werner Held
Annette Oxenius
Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection
description Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.
format article
author Suzanne P. M. Welten
Alexander Yermanos
Nicolas S. Baumann
Franziska Wagen
Nathalie Oetiker
Ioana Sandu
Alessandro Pedrioli
Jennifer D. Oduro
Sai T. Reddy
Luka Cicin-Sain
Werner Held
Annette Oxenius
author_facet Suzanne P. M. Welten
Alexander Yermanos
Nicolas S. Baumann
Franziska Wagen
Nathalie Oetiker
Ioana Sandu
Alessandro Pedrioli
Jennifer D. Oduro
Sai T. Reddy
Luka Cicin-Sain
Werner Held
Annette Oxenius
author_sort Suzanne P. M. Welten
title Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection
title_short Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection
title_full Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection
title_fullStr Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection
title_full_unstemmed Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection
title_sort tcf1+ cells are required to maintain the inflationary t cell pool upon mcmv infection
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ba32f60be74545d6b1590448839902d6
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