Newcastle disease vaccine virus I-2 fails to acquire virulence during repeated passage in vivo [version 2; peer review: 1 approved, 2 approved with reservations]

Newcastle disease vaccine virus I-2 fails to acquire virulence during repeated passage in vivo [version 2; peer review: 1 approved, 2 approved with reservations]

Background This study determined whether the naturally attenuated, thermotolerant Newcastle disease vaccine virus I-2 could acquire virulence after five in vivo passages through SPF chickens. Methods Study design was to international requirements including European Pharmacopoeia, Ph. Eur., v9.0 04/2...

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Autores principales: Shahn P.R. Bisschop, Andrew Peters, Gil Domingue, Michael C. Pearce, Jeanette Verwey, Petrus Poolman
Formato: article
Lenguaje:EN
Publicado: F1000 Research Ltd 2021
Materias:
Medicine
R
Acceso en línea:https://doaj.org/article/ba3df369905e4d888c9a310b26eda6d0
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