Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease
To investigate the effects of chronic hyperglycemia on hippocampal network activity Wirt et al induced sustained hyperglycemia in rats and tested them in a spatial delayed alternation task while recording from the hippocampus and anterior cingulate cortex. They demonstrated that hyperglycemia impair...
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Autores principales: | Ryan. A. Wirt, Lauren. A. Crew, Andrew. A. Ortiz, Adam. M. McNeela, Emmanuel Flores, Jefferson. W. Kinney, James M. Hyman |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/ba44439da3804d76a8fab5796ca4c4fe |
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