Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection

HCV is a virus that can cause chronic infection which can result in a systemic disease that may include many rheumatologic manifestations such as arthritis, myalgia, sicca syndrome, cryoglobulinemia vasculitis as well as other non-rheumatological disorders (renal failure, onco-haematological maligna...

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Autores principales:	Marta Priora, Richard Borrelli, Simone Parisi, Maria Chiara Ditto, Cristina Realmuto, Angela Laganà, Chiara Centanaro Di Vittorio, Rosanna Degiovanni, Clara Lisa Peroni, Enrico Fusaro
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	auto-antibodies hepatitis C virus rheumatological manifestation Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/ba44580d2fbe46e9976e89e77136cd79
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spelling	oai:doaj.org-article:ba44580d2fbe46e9976e89e77136cd792021-11-25T16:46:44ZAutoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection10.3390/biology101110712079-7737https://doaj.org/article/ba44580d2fbe46e9976e89e77136cd792021-10-01T00:00:00Zhttps://www.mdpi.com/2079-7737/10/11/1071https://doaj.org/toc/2079-7737HCV is a virus that can cause chronic infection which can result in a systemic disease that may include many rheumatologic manifestations such as arthritis, myalgia, sicca syndrome, cryoglobulinemia vasculitis as well as other non-rheumatological disorders (renal failure, onco-haematological malignancies). In this population, the high frequency of rheumatoid factor (45–70%), antinuclear (10–40%) and anticardiolipin (15–20%) antibodies is a B-cell mediated finding sustained by the infection. However, the possibility that a primitive rheumatic pathology may coexist with the HCV infection is not to be excluded thus complicating a differential diagnosis between primitive and HCV-related disorders.Marta PrioraRichard BorrelliSimone ParisiMaria Chiara DittoCristina RealmutoAngela LaganàChiara Centanaro Di VittorioRosanna DegiovanniClara Lisa PeroniEnrico FusaroMDPI AGarticleauto-antibodieshepatitis C virusrheumatological manifestationBiology (General)QH301-705.5ENBiology, Vol 10, Iss 1071, p 1071 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	auto-antibodies hepatitis C virus rheumatological manifestation Biology (General) QH301-705.5
spellingShingle	auto-antibodies hepatitis C virus rheumatological manifestation Biology (General) QH301-705.5 Marta Priora Richard Borrelli Simone Parisi Maria Chiara Ditto Cristina Realmuto Angela Laganà Chiara Centanaro Di Vittorio Rosanna Degiovanni Clara Lisa Peroni Enrico Fusaro Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection
description	HCV is a virus that can cause chronic infection which can result in a systemic disease that may include many rheumatologic manifestations such as arthritis, myalgia, sicca syndrome, cryoglobulinemia vasculitis as well as other non-rheumatological disorders (renal failure, onco-haematological malignancies). In this population, the high frequency of rheumatoid factor (45–70%), antinuclear (10–40%) and anticardiolipin (15–20%) antibodies is a B-cell mediated finding sustained by the infection. However, the possibility that a primitive rheumatic pathology may coexist with the HCV infection is not to be excluded thus complicating a differential diagnosis between primitive and HCV-related disorders.
format	article
author	Marta Priora Richard Borrelli Simone Parisi Maria Chiara Ditto Cristina Realmuto Angela Laganà Chiara Centanaro Di Vittorio Rosanna Degiovanni Clara Lisa Peroni Enrico Fusaro
author_facet	Marta Priora Richard Borrelli Simone Parisi Maria Chiara Ditto Cristina Realmuto Angela Laganà Chiara Centanaro Di Vittorio Rosanna Degiovanni Clara Lisa Peroni Enrico Fusaro
author_sort	Marta Priora
title	Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection
title_short	Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection
title_full	Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection
title_fullStr	Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection
title_full_unstemmed	Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection
title_sort	autoantibodies and rheumatologic manifestations in hepatitis c virus infection
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/ba44580d2fbe46e9976e89e77136cd79
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Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection

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