Noise driven evolutionary waves.

Adaptation in spatially extended populations entails the propagation of evolutionary novelties across habitat ranges. Driven by natural selection, beneficial mutations sweep through the population in a "wave of advance". The standard model for these traveling waves, due to R. Fisher and A....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Oskar Hallatschek
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/ba5237c2d1c345199a09fbf0d209949c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ba5237c2d1c345199a09fbf0d209949c
record_format	dspace
spelling	oai:doaj.org-article:ba5237c2d1c345199a09fbf0d209949c2021-11-18T05:50:40ZNoise driven evolutionary waves.1553-734X1553-735810.1371/journal.pcbi.1002005https://doaj.org/article/ba5237c2d1c345199a09fbf0d209949c2011-03-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423714/pdf/?tool=EBIhttps://doaj.org/toc/1553-734Xhttps://doaj.org/toc/1553-7358Adaptation in spatially extended populations entails the propagation of evolutionary novelties across habitat ranges. Driven by natural selection, beneficial mutations sweep through the population in a "wave of advance". The standard model for these traveling waves, due to R. Fisher and A. Kolmogorov, plays an important role in many scientific areas besides evolution, such as ecology, epidemiology, chemical kinetics, and recently even in particle physics. Here, we extend the Fisher-Kolmogorov model to account for mutations that confer an increase in the density of the population, for instance as a result of an improved metabolic efficiency. We show that these mutations invade by the action of random genetic drift, even if the mutations are slightly deleterious. The ensuing class of noise-driven waves are characterized by a wave speed that decreases with increasing population sizes, contrary to conventional Fisher-Kolmogorov waves. When a trade-off exists between density and growth rate, an evolutionary optimal population density can be predicted. Our simulations and analytical results show that genetic drift in conjunction with spatial structure promotes the economical use of limited resources. The simplicity of our model, which lacks any complex interactions between individuals, suggests that noise-induced pattern formation may arise in many complex biological systems including evolution.Oskar HallatschekPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Computational Biology, Vol 7, Iss 3, p e1002005 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Oskar Hallatschek Noise driven evolutionary waves.
description	Adaptation in spatially extended populations entails the propagation of evolutionary novelties across habitat ranges. Driven by natural selection, beneficial mutations sweep through the population in a "wave of advance". The standard model for these traveling waves, due to R. Fisher and A. Kolmogorov, plays an important role in many scientific areas besides evolution, such as ecology, epidemiology, chemical kinetics, and recently even in particle physics. Here, we extend the Fisher-Kolmogorov model to account for mutations that confer an increase in the density of the population, for instance as a result of an improved metabolic efficiency. We show that these mutations invade by the action of random genetic drift, even if the mutations are slightly deleterious. The ensuing class of noise-driven waves are characterized by a wave speed that decreases with increasing population sizes, contrary to conventional Fisher-Kolmogorov waves. When a trade-off exists between density and growth rate, an evolutionary optimal population density can be predicted. Our simulations and analytical results show that genetic drift in conjunction with spatial structure promotes the economical use of limited resources. The simplicity of our model, which lacks any complex interactions between individuals, suggests that noise-induced pattern formation may arise in many complex biological systems including evolution.
format	article
author	Oskar Hallatschek
author_facet	Oskar Hallatschek
author_sort	Oskar Hallatschek
title	Noise driven evolutionary waves.
title_short	Noise driven evolutionary waves.
title_full	Noise driven evolutionary waves.
title_fullStr	Noise driven evolutionary waves.
title_full_unstemmed	Noise driven evolutionary waves.
title_sort	noise driven evolutionary waves.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/ba5237c2d1c345199a09fbf0d209949c
work_keys_str_mv	AT oskarhallatschek noisedrivenevolutionarywaves
_version_	1718424811588288512

Noise driven evolutionary waves.

Ejemplares similares