Determinants of promoter and enhancer transcription directionality in metazoans

Divergent transcription from promoters and enhancers occurs in many species, but it is unclear if it is a general feature of all eukaryotic cis regulatory elements. Here the authors define cis regulatory elements in worms, flies, and human; and identify several differences in regulatory architecture...

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Autores principales:	Mahmoud M. Ibrahim, Aslihan Karabacak, Alexander Glahs, Ena Kolundzic, Antje Hirsekorn, Alexa Carda, Baris Tursun, Robert P. Zinzen, Scott A. Lacadie, Uwe Ohler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ba6afea8491d4c6b9ffb77e4b92a8370
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spelling	oai:doaj.org-article:ba6afea8491d4c6b9ffb77e4b92a83702021-12-02T14:38:52ZDeterminants of promoter and enhancer transcription directionality in metazoans10.1038/s41467-018-06962-z2041-1723https://doaj.org/article/ba6afea8491d4c6b9ffb77e4b92a83702018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06962-zhttps://doaj.org/toc/2041-1723Divergent transcription from promoters and enhancers occurs in many species, but it is unclear if it is a general feature of all eukaryotic cis regulatory elements. Here the authors define cis regulatory elements in worms, flies, and human; and identify several differences in regulatory architecture among metazoans.Mahmoud M. IbrahimAslihan KarabacakAlexander GlahsEna KolundzicAntje HirsekornAlexa CardaBaris TursunRobert P. ZinzenScott A. LacadieUwe OhlerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mahmoud M. Ibrahim Aslihan Karabacak Alexander Glahs Ena Kolundzic Antje Hirsekorn Alexa Carda Baris Tursun Robert P. Zinzen Scott A. Lacadie Uwe Ohler Determinants of promoter and enhancer transcription directionality in metazoans
description	Divergent transcription from promoters and enhancers occurs in many species, but it is unclear if it is a general feature of all eukaryotic cis regulatory elements. Here the authors define cis regulatory elements in worms, flies, and human; and identify several differences in regulatory architecture among metazoans.
format	article
author	Mahmoud M. Ibrahim Aslihan Karabacak Alexander Glahs Ena Kolundzic Antje Hirsekorn Alexa Carda Baris Tursun Robert P. Zinzen Scott A. Lacadie Uwe Ohler
author_facet	Mahmoud M. Ibrahim Aslihan Karabacak Alexander Glahs Ena Kolundzic Antje Hirsekorn Alexa Carda Baris Tursun Robert P. Zinzen Scott A. Lacadie Uwe Ohler
author_sort	Mahmoud M. Ibrahim
title	Determinants of promoter and enhancer transcription directionality in metazoans
title_short	Determinants of promoter and enhancer transcription directionality in metazoans
title_full	Determinants of promoter and enhancer transcription directionality in metazoans
title_fullStr	Determinants of promoter and enhancer transcription directionality in metazoans
title_full_unstemmed	Determinants of promoter and enhancer transcription directionality in metazoans
title_sort	determinants of promoter and enhancer transcription directionality in metazoans
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ba6afea8491d4c6b9ffb77e4b92a8370
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Determinants of promoter and enhancer transcription directionality in metazoans

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