CONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS

In the article using the binomial distribution analysis of the intensity of рориlation antitoxic (AT) and antibacterial (AB) of immunity to diphtheria in terms of specific diphtheria antibodies in the sera of healthy adults aged 20 to 51 years and. older, living in Russia and. Italy. The latter, in...

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Autores principales: E. A. Shmeleva, S. M. Popkova, T. N. Flrsova, E. B. Rakova, L. V. Serdyuk, M. M. Gubin
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Acceso en línea:https://doaj.org/article/ba6db632fc664759a4a32cca38ab6ff0
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spelling oai:doaj.org-article:ba6db632fc664759a4a32cca38ab6ff02021-11-23T06:14:23ZCONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS2541-94202587-9596https://doaj.org/article/ba6db632fc664759a4a32cca38ab6ff02012-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1113https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596In the article using the binomial distribution analysis of the intensity of рориlation antitoxic (AT) and antibacterial (AB) of immunity to diphtheria in terms of specific diphtheria antibodies in the sera of healthy adults aged 20 to 51 years and. older, living in Russia and. Italy. The latter, in contrast to Russia, during the epidemic was only a few cases of diphtheria. For the population of people from Italy the optimal parameters of tension antibody immunity (bimodal distribution of the concentrations of AT antibodies) are determined, whereas for the adult population of Russia experienced an abnormally high, overvoltages antibody immunity (lack of bimodal distribution). The level of concentration of antibody isotypes AB M, G, A in both countries match the total synthesis of immunoglobulin isotypes in the ontogeny of these: thus, in the sera of adults aged 20 to 40 years AB antibody IgG prevail. Low concentrations of antitoxin in the blood of most adults living in Italy, recharged high AB IgG in these same serum, and. optimal concentrations of AB IgM and. IgA. This indicates the possibility lifting the mass revaccination of adults, and. creating an individual approach to their boosters. Optimal bimodal distribution of AB antibodies in the population of healthy adults, both in Russia and. in Italy, is an additional protection to the diphtheria antitoxic resistance.E. A. ShmelevaS. M. PopkovaT. N. FlrsovaE. B. RakovaL. V. SerdyukM. M. GubinScientific Сentre for Family Health and Human Reproduction Problemsarticlediphtheria immunizationsantitoxic antibodiesanti-bacterial antibodiespopulation analysisa bimodal distributionScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5(1), Pp 145-150 (2012)
institution DOAJ
collection DOAJ
language RU
topic diphtheria immunizations
antitoxic antibodies
anti-bacterial antibodies
population analysis
a bimodal distribution
Science
Q
spellingShingle diphtheria immunizations
antitoxic antibodies
anti-bacterial antibodies
population analysis
a bimodal distribution
Science
Q
E. A. Shmeleva
S. M. Popkova
T. N. Flrsova
E. B. Rakova
L. V. Serdyuk
M. M. Gubin
CONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS
description In the article using the binomial distribution analysis of the intensity of рориlation antitoxic (AT) and antibacterial (AB) of immunity to diphtheria in terms of specific diphtheria antibodies in the sera of healthy adults aged 20 to 51 years and. older, living in Russia and. Italy. The latter, in contrast to Russia, during the epidemic was only a few cases of diphtheria. For the population of people from Italy the optimal parameters of tension antibody immunity (bimodal distribution of the concentrations of AT antibodies) are determined, whereas for the adult population of Russia experienced an abnormally high, overvoltages antibody immunity (lack of bimodal distribution). The level of concentration of antibody isotypes AB M, G, A in both countries match the total synthesis of immunoglobulin isotypes in the ontogeny of these: thus, in the sera of adults aged 20 to 40 years AB antibody IgG prevail. Low concentrations of antitoxin in the blood of most adults living in Italy, recharged high AB IgG in these same serum, and. optimal concentrations of AB IgM and. IgA. This indicates the possibility lifting the mass revaccination of adults, and. creating an individual approach to their boosters. Optimal bimodal distribution of AB antibodies in the population of healthy adults, both in Russia and. in Italy, is an additional protection to the diphtheria antitoxic resistance.
format article
author E. A. Shmeleva
S. M. Popkova
T. N. Flrsova
E. B. Rakova
L. V. Serdyuk
M. M. Gubin
author_facet E. A. Shmeleva
S. M. Popkova
T. N. Flrsova
E. B. Rakova
L. V. Serdyuk
M. M. Gubin
author_sort E. A. Shmeleva
title CONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS
title_short CONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS
title_full CONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS
title_fullStr CONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS
title_full_unstemmed CONTENTS DIPHTHERIA ANTITOXIC AND ANTIBACTERIAL ANTIBODIES IN THE SERUM OF HEALTHY ADULTS
title_sort contents diphtheria antitoxic and antibacterial antibodies in the serum of healthy adults
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2012
url https://doaj.org/article/ba6db632fc664759a4a32cca38ab6ff0
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