Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus

Aim. To measure Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus (DM), elucidate its relationship with clinical manifestationsof the disease and biochemical blood characteristics. Materials and methods. A total of 76 DM patients were enrolled in this study (39 with DM1 and...

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Autores principales:	Z M Shamansurova, F A Mukhamedova, A G Tsoi, A B Tashmanova, A V Alieva, N A Akhrarova
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2009
Materias:	na-k-atpase electrolyte gradient across plasma membrane c peptide diabetic neuropathy Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/ba6ea2b9bd4a40ea96ecbed41c172bc2
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id	oai:doaj.org-article:ba6ea2b9bd4a40ea96ecbed41c172bc2
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spelling	oai:doaj.org-article:ba6ea2b9bd4a40ea96ecbed41c172bc22021-11-14T09:00:13ZAbnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus2072-03512072-037810.14341/2072-0351-5399https://doaj.org/article/ba6ea2b9bd4a40ea96ecbed41c172bc22009-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5399https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To measure Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus (DM), elucidate its relationship with clinical manifestationsof the disease and biochemical blood characteristics. Materials and methods. A total of 76 DM patients were enrolled in this study (39 with DM1 and 35 with DM2). Control group consisted of 11 subjectswithout DM. They were examined for HbA1c, nitrite and nitrate levels in blood and membranes, sialidase activity in erythrocytes and Na-KATPaseactivity measured from variations of inorganic phosphorus content in the presence of ATP. Results. Na-K-ATPase activity in MD patients was significantly lower than in controls (pZ M ShamansurovaF A MukhamedovaA G TsoiA B TashmanovaA V AlievaN A AkhrarovaEndocrinology Research Centrearticlena-k-atpaseelectrolyte gradient across plasma membranec peptidediabetic neuropathyNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 12, Iss 2, Pp 55-57 (2009)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	na-k-atpase electrolyte gradient across plasma membrane c peptide diabetic neuropathy Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	na-k-atpase electrolyte gradient across plasma membrane c peptide diabetic neuropathy Nutritional diseases. Deficiency diseases RC620-627 Z M Shamansurova F A Mukhamedova A G Tsoi A B Tashmanova A V Alieva N A Akhrarova Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
description	Aim. To measure Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus (DM), elucidate its relationship with clinical manifestationsof the disease and biochemical blood characteristics. Materials and methods. A total of 76 DM patients were enrolled in this study (39 with DM1 and 35 with DM2). Control group consisted of 11 subjectswithout DM. They were examined for HbA1c, nitrite and nitrate levels in blood and membranes, sialidase activity in erythrocytes and Na-KATPaseactivity measured from variations of inorganic phosphorus content in the presence of ATP. Results. Na-K-ATPase activity in MD patients was significantly lower than in controls (p
format	article
author	Z M Shamansurova F A Mukhamedova A G Tsoi A B Tashmanova A V Alieva N A Akhrarova
author_facet	Z M Shamansurova F A Mukhamedova A G Tsoi A B Tashmanova A V Alieva N A Akhrarova
author_sort	Z M Shamansurova
title	Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
title_short	Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
title_full	Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
title_fullStr	Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
title_full_unstemmed	Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
title_sort	abnormal na-k-atpase activity in erythrocytes from patients with diabetes mellitus
publisher	Endocrinology Research Centre
publishDate	2009
url	https://doaj.org/article/ba6ea2b9bd4a40ea96ecbed41c172bc2
work_keys_str_mv	AT zmshamansurova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT famukhamedova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT agtsoi abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT abtashmanova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT avalieva abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT naakhrarova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus
_version_	1718429675676499968

Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus

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