A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes

Regulators of the important ubiquitylation cascade are not well studied. Here, the authors report the crystal structure of a prenylated membrane-anchored ubiquitin-fold protein from Arabidopsisbound to an E2 protein and conclude that it is an example of selective activation between E2 enzymes.

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Autores principales:	Xiaolong Lu, Konstantin R. Malley, Caitlin C. Brenner, Olga Koroleva, Sergey Korolev, Brian P. Downes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ba8ab800ee01437e95b50a46ccc7136a
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spelling	oai:doaj.org-article:ba8ab800ee01437e95b50a46ccc7136a2021-12-02T16:49:59ZA MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes10.1038/ncomms125802041-1723https://doaj.org/article/ba8ab800ee01437e95b50a46ccc7136a2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12580https://doaj.org/toc/2041-1723Regulators of the important ubiquitylation cascade are not well studied. Here, the authors report the crystal structure of a prenylated membrane-anchored ubiquitin-fold protein from Arabidopsisbound to an E2 protein and conclude that it is an example of selective activation between E2 enzymes.Xiaolong LuKonstantin R. MalleyCaitlin C. BrennerOlga KorolevaSergey KorolevBrian P. DownesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaolong Lu Konstantin R. Malley Caitlin C. Brenner Olga Koroleva Sergey Korolev Brian P. Downes A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes
description	Regulators of the important ubiquitylation cascade are not well studied. Here, the authors report the crystal structure of a prenylated membrane-anchored ubiquitin-fold protein from Arabidopsisbound to an E2 protein and conclude that it is an example of selective activation between E2 enzymes.
format	article
author	Xiaolong Lu Konstantin R. Malley Caitlin C. Brenner Olga Koroleva Sergey Korolev Brian P. Downes
author_facet	Xiaolong Lu Konstantin R. Malley Caitlin C. Brenner Olga Koroleva Sergey Korolev Brian P. Downes
author_sort	Xiaolong Lu
title	A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes
title_short	A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes
title_full	A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes
title_fullStr	A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes
title_full_unstemmed	A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes
title_sort	mub e2 structure reveals e1 selectivity between cognate ubiquitin e2s in eukaryotes
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/ba8ab800ee01437e95b50a46ccc7136a
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A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes

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