AAV2.7m8 is a powerful viral vector for inner ear gene therapy
Adeno-associated virus is used in gene therapy in mouse models of hearing loss. Here the authors compare vectors and find AAV2.7m8 can infect cells in the inner ear with high efficiency.
Guardado en:
Autores principales: | , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ba8b27d6ee8346729a61ab90b8950373 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:ba8b27d6ee8346729a61ab90b8950373 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:ba8b27d6ee8346729a61ab90b89503732021-12-02T17:02:11ZAAV2.7m8 is a powerful viral vector for inner ear gene therapy10.1038/s41467-018-08243-12041-1723https://doaj.org/article/ba8b27d6ee8346729a61ab90b89503732019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08243-1https://doaj.org/toc/2041-1723Adeno-associated virus is used in gene therapy in mouse models of hearing loss. Here the authors compare vectors and find AAV2.7m8 can infect cells in the inner ear with high efficiency.Kevin IsgrigDevin S. McDougaldJianliang ZhuHong Jun WangJean BennettWade W. ChienNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Kevin Isgrig Devin S. McDougald Jianliang Zhu Hong Jun Wang Jean Bennett Wade W. Chien AAV2.7m8 is a powerful viral vector for inner ear gene therapy |
description |
Adeno-associated virus is used in gene therapy in mouse models of hearing loss. Here the authors compare vectors and find AAV2.7m8 can infect cells in the inner ear with high efficiency. |
format |
article |
author |
Kevin Isgrig Devin S. McDougald Jianliang Zhu Hong Jun Wang Jean Bennett Wade W. Chien |
author_facet |
Kevin Isgrig Devin S. McDougald Jianliang Zhu Hong Jun Wang Jean Bennett Wade W. Chien |
author_sort |
Kevin Isgrig |
title |
AAV2.7m8 is a powerful viral vector for inner ear gene therapy |
title_short |
AAV2.7m8 is a powerful viral vector for inner ear gene therapy |
title_full |
AAV2.7m8 is a powerful viral vector for inner ear gene therapy |
title_fullStr |
AAV2.7m8 is a powerful viral vector for inner ear gene therapy |
title_full_unstemmed |
AAV2.7m8 is a powerful viral vector for inner ear gene therapy |
title_sort |
aav2.7m8 is a powerful viral vector for inner ear gene therapy |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/ba8b27d6ee8346729a61ab90b8950373 |
work_keys_str_mv |
AT kevinisgrig aav27m8isapowerfulviralvectorforinnereargenetherapy AT devinsmcdougald aav27m8isapowerfulviralvectorforinnereargenetherapy AT jianliangzhu aav27m8isapowerfulviralvectorforinnereargenetherapy AT hongjunwang aav27m8isapowerfulviralvectorforinnereargenetherapy AT jeanbennett aav27m8isapowerfulviralvectorforinnereargenetherapy AT wadewchien aav27m8isapowerfulviralvectorforinnereargenetherapy |
_version_ |
1718381930447110144 |