AAV2.7m8 is a powerful viral vector for inner ear gene therapy

Adeno-associated virus is used in gene therapy in mouse models of hearing loss. Here the authors compare vectors and find AAV2.7m8 can infect cells in the inner ear with high efficiency.

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Autores principales: Kevin Isgrig, Devin S. McDougald, Jianliang Zhu, Hong Jun Wang, Jean Bennett, Wade W. Chien
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
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Acceso en línea:https://doaj.org/article/ba8b27d6ee8346729a61ab90b8950373
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spelling oai:doaj.org-article:ba8b27d6ee8346729a61ab90b89503732021-12-02T17:02:11ZAAV2.7m8 is a powerful viral vector for inner ear gene therapy10.1038/s41467-018-08243-12041-1723https://doaj.org/article/ba8b27d6ee8346729a61ab90b89503732019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08243-1https://doaj.org/toc/2041-1723Adeno-associated virus is used in gene therapy in mouse models of hearing loss. Here the authors compare vectors and find AAV2.7m8 can infect cells in the inner ear with high efficiency.Kevin IsgrigDevin S. McDougaldJianliang ZhuHong Jun WangJean BennettWade W. ChienNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kevin Isgrig
Devin S. McDougald
Jianliang Zhu
Hong Jun Wang
Jean Bennett
Wade W. Chien
AAV2.7m8 is a powerful viral vector for inner ear gene therapy
description Adeno-associated virus is used in gene therapy in mouse models of hearing loss. Here the authors compare vectors and find AAV2.7m8 can infect cells in the inner ear with high efficiency.
format article
author Kevin Isgrig
Devin S. McDougald
Jianliang Zhu
Hong Jun Wang
Jean Bennett
Wade W. Chien
author_facet Kevin Isgrig
Devin S. McDougald
Jianliang Zhu
Hong Jun Wang
Jean Bennett
Wade W. Chien
author_sort Kevin Isgrig
title AAV2.7m8 is a powerful viral vector for inner ear gene therapy
title_short AAV2.7m8 is a powerful viral vector for inner ear gene therapy
title_full AAV2.7m8 is a powerful viral vector for inner ear gene therapy
title_fullStr AAV2.7m8 is a powerful viral vector for inner ear gene therapy
title_full_unstemmed AAV2.7m8 is a powerful viral vector for inner ear gene therapy
title_sort aav2.7m8 is a powerful viral vector for inner ear gene therapy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/ba8b27d6ee8346729a61ab90b8950373
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AT hongjunwang aav27m8isapowerfulviralvectorforinnereargenetherapy
AT jeanbennett aav27m8isapowerfulviralvectorforinnereargenetherapy
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