Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders

James M Greenblatt1, Craig Sussman1, Mariko Jameson1, Lee Yuan1, Daniel A Hoffman2, Dan V Iosifescu31Comprehensive Psychiatric Resources, Waltham, MA, USA; 2Neuro-Therapy Clinic Inc, Denver, CO, USA; 3Mood and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY, USABackground: A...

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Autores principales: Greenblatt JM, Sussman C, Jameson M, Yuan L, Hoffman DA, Iosifescu DV
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Publicado: Dove Medical Press 2011
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spelling oai:doaj.org-article:ba9b2c4ae2964571aa40e555a9f9722c2021-12-02T05:49:15ZRetrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders1176-63281178-2021https://doaj.org/article/ba9b2c4ae2964571aa40e555a9f9722c2011-09-01T00:00:00Zhttp://www.dovepress.com/retrospective-chart-review-of-a-referenced-eeg-database-in-assisting-m-a8263https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021James M Greenblatt1, Craig Sussman1, Mariko Jameson1, Lee Yuan1, Daniel A Hoffman2, Dan V Iosifescu31Comprehensive Psychiatric Resources, Waltham, MA, USA; 2Neuro-Therapy Clinic Inc, Denver, CO, USA; 3Mood and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY, USABackground: A retrospective chart review was undertaken in a private clinic to examine the clinical outcomes for patients with an eating disorder comorbid with depression or bipolar illness who underwent a referenced electroencephalographic (EEG) database analysis to help guide medication selection.Method: We examined 33 charts for patients with the primary psychiatric diagnosis of an eating disorder and comorbid major depressive disorder or bipolar disorder who underwent a quantitative EEG database assessment to provide additional information for choices of medication. The current analysis includes data from 22 subjects who accepted treatments based on information from the referenced-EEG medication database. Hamilton Depression Rating Scale, Clinical Global Impression-Severity, Clinical Global Impression-Improvement, and hospitalization data were examined for these patients.Results: Patients whose EEG data was used for clinical treatment reported significant decreases in associated depressive symptoms (HDRS scores), overall severity of illness (Clinical Global Impression-Severity), and overall clinical global improvement (Clinical Global Impression-Improvement). This cohort also reported fewer inpatient, residential, and partial hospitalization program days following referenced-EEG compared with the two-year period prior to treatment.Conclusion: These findings are consistent with previously reported data for patients with eating disorders and suggest the need for future studies using EEG data correlated with those from other patients with similar quantitative EEG features.Keywords: eating disorders, anorexia, bulimia, depression, referenced-EEG, chart reviewGreenblatt JMSussman CJameson MYuan LHoffman DAIosifescu DVDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2011, Iss Issue 1, Pp 529-541 (2011)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Greenblatt JM
Sussman C
Jameson M
Yuan L
Hoffman DA
Iosifescu DV
Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders
description James M Greenblatt1, Craig Sussman1, Mariko Jameson1, Lee Yuan1, Daniel A Hoffman2, Dan V Iosifescu31Comprehensive Psychiatric Resources, Waltham, MA, USA; 2Neuro-Therapy Clinic Inc, Denver, CO, USA; 3Mood and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY, USABackground: A retrospective chart review was undertaken in a private clinic to examine the clinical outcomes for patients with an eating disorder comorbid with depression or bipolar illness who underwent a referenced electroencephalographic (EEG) database analysis to help guide medication selection.Method: We examined 33 charts for patients with the primary psychiatric diagnosis of an eating disorder and comorbid major depressive disorder or bipolar disorder who underwent a quantitative EEG database assessment to provide additional information for choices of medication. The current analysis includes data from 22 subjects who accepted treatments based on information from the referenced-EEG medication database. Hamilton Depression Rating Scale, Clinical Global Impression-Severity, Clinical Global Impression-Improvement, and hospitalization data were examined for these patients.Results: Patients whose EEG data was used for clinical treatment reported significant decreases in associated depressive symptoms (HDRS scores), overall severity of illness (Clinical Global Impression-Severity), and overall clinical global improvement (Clinical Global Impression-Improvement). This cohort also reported fewer inpatient, residential, and partial hospitalization program days following referenced-EEG compared with the two-year period prior to treatment.Conclusion: These findings are consistent with previously reported data for patients with eating disorders and suggest the need for future studies using EEG data correlated with those from other patients with similar quantitative EEG features.Keywords: eating disorders, anorexia, bulimia, depression, referenced-EEG, chart review
format article
author Greenblatt JM
Sussman C
Jameson M
Yuan L
Hoffman DA
Iosifescu DV
author_facet Greenblatt JM
Sussman C
Jameson M
Yuan L
Hoffman DA
Iosifescu DV
author_sort Greenblatt JM
title Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders
title_short Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders
title_full Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders
title_fullStr Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders
title_full_unstemmed Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders
title_sort retrospective chart review of a referenced eeg database in assisting medication selection for treatment of depression in patients with eating disorders
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/ba9b2c4ae2964571aa40e555a9f9722c
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