A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

<h4>Introduction</h4>Circulating cell-free DNA (cf-DNA) is a useful indicator of cell death, and it can also be used to predict outcomes in various clinical disorders. Several innate immune mechanisms are known to be involved in eliminating DNA and chromatin-related material as part of t...

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Main Authors: Juulia Jylhävä, Leo-Pekka Lyytikäinen, Mika Kähönen, Nina Hutri-Kähönen, Johannes Kettunen, Jorma Viikari, Olli T Raitakari, Terho Lehtimäki, Mikko Hurme
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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R
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Online Access:https://doaj.org/article/ba9d5a5af5dd443b8e8ef0cdec5a09d9
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