Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

mTORC1 is a critical kinase that regulates cell growth and proliferation. Here the authors show that glutamine metabolism is sufficient to restore mTORC1 activity during prolonged amino acid starvation in an autophagy-dependent manner.

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Detalles Bibliográficos
Autores principales: Hayden Weng Siong Tan, Arthur Yi Loong Sim, Yun Chau Long
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/baa64e48583c47e993cde6f66f813394
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