Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy

Background and Objective: Hemodynamic changes following laryngoscopy and intubation of trachea is one of the main problems in anesthesia. Different methods and drugs are used to lower this problem. The aim of this study was to survey the effect of Alfentanil, which is a short acting opioid on hemody...

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Autores principales:	MA Ropani, H Alreza, F Safari, M Mir, E Alijan Pour
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2005
Materias:	alfentanil blood pressure heart rate laryngoscopy intubation induction Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/baa71841b59646cd8f6dbc59fb0a465e
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id	oai:doaj.org-article:baa71841b59646cd8f6dbc59fb0a465e
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spelling	oai:doaj.org-article:baa71841b59646cd8f6dbc59fb0a465e2021-11-10T09:14:32ZEffect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy1561-41072251-7170https://doaj.org/article/baa71841b59646cd8f6dbc59fb0a465e2005-04-01T00:00:00Zhttp://jbums.org/article-1-2631-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Hemodynamic changes following laryngoscopy and intubation of trachea is one of the main problems in anesthesia. Different methods and drugs are used to lower this problem. The aim of this study was to survey the effect of Alfentanil, which is a short acting opioid on hemodynamic changes. Methods: 100 patients with ASA class I were divided into 2 groups of 50 patients. Both groups received diazepam 0.1 mg/kg, morphine 0.1 mg/kg and faxedil 20 mg/kg as premedication. 3 minutes before induction, Alfentanil group received 10 mg/kg Alfentanil and control group received normal saline as placebo. Both groups received sodium thiopental and succinyl choline for induction. Blood pressure and heart rate were recorded before and after premedication, 1, 3 and 5 minutes after intubation of trachea. The data were compared together. Findings: Changes in heart rate and blood pressure (Systolic and diastolic) before and after premedication had no meaningful difference in both groups, but average of changes in heart rate and blood pressure in the patients in the Alfentanil group after laryngoscopy and intubations were less and there was statistically significant difference. Hemodynamic features in both groups after 5 minutes were stable. Conclusion: According to the results, Alfentanil is effective in reducing heart rate and blood pressure (Systolic and diastolic) after laryngoscopy and intubations of trachea. So, using Alfentanil before laryngoscopy in general anesthesia is recommended.MA RopaniH AlrezaF SafariM MirE Alijan PourBabol University of Medical Sciencesarticlealfentanilblood pressureheart ratelaryngoscopyintubation inductionMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 2, Pp 14-17 (2005)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	alfentanil blood pressure heart rate laryngoscopy intubation induction Medicine R Medicine (General) R5-920
spellingShingle	alfentanil blood pressure heart rate laryngoscopy intubation induction Medicine R Medicine (General) R5-920 MA Ropani H Alreza F Safari M Mir E Alijan Pour Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy
description	Background and Objective: Hemodynamic changes following laryngoscopy and intubation of trachea is one of the main problems in anesthesia. Different methods and drugs are used to lower this problem. The aim of this study was to survey the effect of Alfentanil, which is a short acting opioid on hemodynamic changes. Methods: 100 patients with ASA class I were divided into 2 groups of 50 patients. Both groups received diazepam 0.1 mg/kg, morphine 0.1 mg/kg and faxedil 20 mg/kg as premedication. 3 minutes before induction, Alfentanil group received 10 mg/kg Alfentanil and control group received normal saline as placebo. Both groups received sodium thiopental and succinyl choline for induction. Blood pressure and heart rate were recorded before and after premedication, 1, 3 and 5 minutes after intubation of trachea. The data were compared together. Findings: Changes in heart rate and blood pressure (Systolic and diastolic) before and after premedication had no meaningful difference in both groups, but average of changes in heart rate and blood pressure in the patients in the Alfentanil group after laryngoscopy and intubations were less and there was statistically significant difference. Hemodynamic features in both groups after 5 minutes were stable. Conclusion: According to the results, Alfentanil is effective in reducing heart rate and blood pressure (Systolic and diastolic) after laryngoscopy and intubations of trachea. So, using Alfentanil before laryngoscopy in general anesthesia is recommended.
format	article
author	MA Ropani H Alreza F Safari M Mir E Alijan Pour
author_facet	MA Ropani H Alreza F Safari M Mir E Alijan Pour
author_sort	MA Ropani
title	Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy
title_short	Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy
title_full	Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy
title_fullStr	Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy
title_full_unstemmed	Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy
title_sort	effect of alfentanil on the hemodynamic changes (heart rate, blood pressure) following laryngoscopy
publisher	Babol University of Medical Sciences
publishDate	2005
url	https://doaj.org/article/baa71841b59646cd8f6dbc59fb0a465e
work_keys_str_mv	AT maropani effectofalfentanilonthehemodynamicchangesheartratebloodpressurefollowinglaryngoscopy AT halreza effectofalfentanilonthehemodynamicchangesheartratebloodpressurefollowinglaryngoscopy AT fsafari effectofalfentanilonthehemodynamicchangesheartratebloodpressurefollowinglaryngoscopy AT mmir effectofalfentanilonthehemodynamicchangesheartratebloodpressurefollowinglaryngoscopy AT ealijanpour effectofalfentanilonthehemodynamicchangesheartratebloodpressurefollowinglaryngoscopy
_version_	1718440228044144640

Effect of Alfentanil on the hemodynamic changes (Heart rate, blood pressure) following laryngoscopy

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