Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study

Aisha Al Busaidi,1 Kashinatha Shenoy,1 Sathiya Murthi Panchatcharam,2 Abdullah Al-Mujaini1,3 1Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Oman; 2Research Section, Oman Medical Specialty Board, Muscat, Oman; 3College of Medicine and Health Sciences, Sultan Qaboos Universit...

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Autores principales:	Al Busaidi A, Shenoy K, Panchatcharam S, Al-Mujaini A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	slt race outcome open-angle glaucoma ocular hypertension Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/bab08700f73d4862b6554608e1fac767
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spelling	oai:doaj.org-article:bab08700f73d4862b6554608e1fac7672021-12-02T03:50:37ZShort-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study1177-5483https://doaj.org/article/bab08700f73d4862b6554608e1fac7672020-09-01T00:00:00Zhttps://www.dovepress.com/short-term-efficacy-of-selective-laser-trabeculoplasty-in-omani-eyes-w-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Aisha Al Busaidi,1 Kashinatha Shenoy,1 Sathiya Murthi Panchatcharam,2 Abdullah Al-Mujaini1,3 1Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Oman; 2Research Section, Oman Medical Specialty Board, Muscat, Oman; 3College of Medicine and Health Sciences, Sultan Qaboos University Hospital, Muscat, OmanCorrespondence: Aisha Al Busaidi Department of OphthalmologySultan Qaboos University Hospital, PO Box 38, PC 123, Muscat, OmanTel +968 24144547Email aisha.albusaidi@gmail.comPurpose: There is some evidence suggesting a different nature of response to selective laser trabeculoplasty (SLT) among different races. Therefore, we aimed to assess the short-term efficacy, safety and nature of outcome of SLT in Omani eyes.Patients and Methods: A retrospective review was performed of patients with open-angle glaucoma (OAG) or ocular hypertension (OHTN) who underwent a single session of 360-degree SLT between January 1, 2017 and December 31, 2018. The main outcome was mean IOP reduction and attainment of treatment success at 5 weeks and 12 weeks post treatment defined as at least 20% IOP reduction from baseline without further medications or interventions. Secondary outcomes were frequency of adverse events and factors predicting success.Results: A total of 33 eyes of 33 Omani patients who underwent treatment with SLT were analyzed. The nature of response to laser followed a gradual pattern as the mean IOP reduction from baseline was 20.2% (5.21 mm Hg, P < 0.001) at 5 weeks and further enhanced to 27.2% (6.95 mm Hg, P < 0.001) at 12 weeks. Short-term success was achieved in 51.5% and 72.2% of eyes at 5 and 12 weeks, respectively. SLT was most effective in OHTN subgroup and those with higher baseline IOP (both P < 0.001). Side effects were an infrequent occurrence, minor and transient.Conclusion: The short-term success of SLT in Omani eyes was clinically relevant and comparable to the gradual pattern seen in patients of Indian ancestry. It is a safe therapeutic option in selective Omani eyes.Keywords: SLT, race, outcome, open-angle glaucoma, ocular hypertensionAl Busaidi AShenoy KPanchatcharam SAl-Mujaini ADove Medical Pressarticlesltraceoutcomeopen-angle glaucomaocular hypertensionOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 2631-2638 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	slt race outcome open-angle glaucoma ocular hypertension Ophthalmology RE1-994
spellingShingle	slt race outcome open-angle glaucoma ocular hypertension Ophthalmology RE1-994 Al Busaidi A Shenoy K Panchatcharam S Al-Mujaini A Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study
description	Aisha Al Busaidi,1 Kashinatha Shenoy,1 Sathiya Murthi Panchatcharam,2 Abdullah Al-Mujaini1,3 1Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Oman; 2Research Section, Oman Medical Specialty Board, Muscat, Oman; 3College of Medicine and Health Sciences, Sultan Qaboos University Hospital, Muscat, OmanCorrespondence: Aisha Al Busaidi Department of OphthalmologySultan Qaboos University Hospital, PO Box 38, PC 123, Muscat, OmanTel +968 24144547Email aisha.albusaidi@gmail.comPurpose: There is some evidence suggesting a different nature of response to selective laser trabeculoplasty (SLT) among different races. Therefore, we aimed to assess the short-term efficacy, safety and nature of outcome of SLT in Omani eyes.Patients and Methods: A retrospective review was performed of patients with open-angle glaucoma (OAG) or ocular hypertension (OHTN) who underwent a single session of 360-degree SLT between January 1, 2017 and December 31, 2018. The main outcome was mean IOP reduction and attainment of treatment success at 5 weeks and 12 weeks post treatment defined as at least 20% IOP reduction from baseline without further medications or interventions. Secondary outcomes were frequency of adverse events and factors predicting success.Results: A total of 33 eyes of 33 Omani patients who underwent treatment with SLT were analyzed. The nature of response to laser followed a gradual pattern as the mean IOP reduction from baseline was 20.2% (5.21 mm Hg, P < 0.001) at 5 weeks and further enhanced to 27.2% (6.95 mm Hg, P < 0.001) at 12 weeks. Short-term success was achieved in 51.5% and 72.2% of eyes at 5 and 12 weeks, respectively. SLT was most effective in OHTN subgroup and those with higher baseline IOP (both P < 0.001). Side effects were an infrequent occurrence, minor and transient.Conclusion: The short-term success of SLT in Omani eyes was clinically relevant and comparable to the gradual pattern seen in patients of Indian ancestry. It is a safe therapeutic option in selective Omani eyes.Keywords: SLT, race, outcome, open-angle glaucoma, ocular hypertension
format	article
author	Al Busaidi A Shenoy K Panchatcharam S Al-Mujaini A
author_facet	Al Busaidi A Shenoy K Panchatcharam S Al-Mujaini A
author_sort	Al Busaidi A
title	Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study
title_short	Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study
title_full	Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study
title_fullStr	Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study
title_full_unstemmed	Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study
title_sort	short-term efficacy of selective laser trabeculoplasty in omani eyes with glaucoma: a single institutional study
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/bab08700f73d4862b6554608e1fac767
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_version_	1718401613946683392

Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study

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