Immune modulatory effects of oncogenic KRAS in cancer
Oncogenic signalling has been historically associated with sustained cancer cell-intrinsic proliferation, however its role in promoting tumour immunoresistance has also become evident. Here, Hamarsheh and colleagues review and discuss the preclinical work on the immune modulatory effects of oncogeni...
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Nature Portfolio
2020
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oai:doaj.org-article:bab2055f90cc4a4aa21071e579d430b62021-12-02T14:40:41ZImmune modulatory effects of oncogenic KRAS in cancer10.1038/s41467-020-19288-62041-1723https://doaj.org/article/bab2055f90cc4a4aa21071e579d430b62020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19288-6https://doaj.org/toc/2041-1723Oncogenic signalling has been historically associated with sustained cancer cell-intrinsic proliferation, however its role in promoting tumour immunoresistance has also become evident. Here, Hamarsheh and colleagues review and discuss the preclinical work on the immune modulatory effects of oncogenic KRAS and the potential clinical application.Shaima’a HamarshehOlaf GroßTilman BrummerRobert ZeiserNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Shaima’a Hamarsheh Olaf Groß Tilman Brummer Robert Zeiser Immune modulatory effects of oncogenic KRAS in cancer |
description |
Oncogenic signalling has been historically associated with sustained cancer cell-intrinsic proliferation, however its role in promoting tumour immunoresistance has also become evident. Here, Hamarsheh and colleagues review and discuss the preclinical work on the immune modulatory effects of oncogenic KRAS and the potential clinical application. |
format |
article |
author |
Shaima’a Hamarsheh Olaf Groß Tilman Brummer Robert Zeiser |
author_facet |
Shaima’a Hamarsheh Olaf Groß Tilman Brummer Robert Zeiser |
author_sort |
Shaima’a Hamarsheh |
title |
Immune modulatory effects of oncogenic KRAS in cancer |
title_short |
Immune modulatory effects of oncogenic KRAS in cancer |
title_full |
Immune modulatory effects of oncogenic KRAS in cancer |
title_fullStr |
Immune modulatory effects of oncogenic KRAS in cancer |
title_full_unstemmed |
Immune modulatory effects of oncogenic KRAS in cancer |
title_sort |
immune modulatory effects of oncogenic kras in cancer |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/bab2055f90cc4a4aa21071e579d430b6 |
work_keys_str_mv |
AT shaimaahamarsheh immunemodulatoryeffectsofoncogenickrasincancer AT olafgroß immunemodulatoryeffectsofoncogenickrasincancer AT tilmanbrummer immunemodulatoryeffectsofoncogenickrasincancer AT robertzeiser immunemodulatoryeffectsofoncogenickrasincancer |
_version_ |
1718390194043879424 |