Asymptomatic hyponatremia precipitated by COVID-19 pneumonia

COVID-19, also known as SARS-CoV-2, which originated in China in late 2019, has spread rapidly resulting in a global pandemic. COVID-19 has been linked to many different clinical manifestations, including hyponatremia. The cause of hyponatremia in acute COVID-19 infection is speculated to be multifa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Abhinandan R. Chittal, Shiavax J. Rao, Pallavi Lakra, Mary E. Zulty
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	covid-19 hyponatremia siadh hypotonic hyponatremia interleukin Internal medicine RC31-1245
Acceso en línea:	https://doaj.org/article/bab9b76c900e437581b5638b0f785389
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:bab9b76c900e437581b5638b0f785389
record_format	dspace
spelling	oai:doaj.org-article:bab9b76c900e437581b5638b0f7853892021-11-17T14:21:57ZAsymptomatic hyponatremia precipitated by COVID-19 pneumonia2000-966610.1080/20009666.2021.1979738https://doaj.org/article/bab9b76c900e437581b5638b0f7853892021-11-01T00:00:00Zhttp://dx.doi.org/10.1080/20009666.2021.1979738https://doaj.org/toc/2000-9666COVID-19, also known as SARS-CoV-2, which originated in China in late 2019, has spread rapidly resulting in a global pandemic. COVID-19 has been linked to many different clinical manifestations, including hyponatremia. The cause of hyponatremia in acute COVID-19 infection is speculated to be multifactorial, including syndrome of inappropriate antidiuretic hormone secretion (SIADH), thought to be a result of inflammatory cytokines (Interleukin-6) and/or related to the gastrointestinal symptoms of this infection. SIADH in the setting of COVID-19 pneumonia is an established complication of this disease. This is the case of an 81-year-old woman with a history of hypertension, on thiazide diuretic, initially presented after a fall in the setting of COVID-19 pneumonia. She was treated with remdesivir and dexamethasone and then discharged to a rehab facility with normal labwork, including a sodium of 137 mmol/L. Two weeks later, routine labwork identified hyponatremia of 111 mmol/L. Her vital signs were normal, she was euvolemic on exam and alert/oriented with no complaints. Investigations into the etiology of her hyponatremia included a urine sodium of 72 mmol/L, serum osmolality of 231 mOsm/kg, urine osmolality of 454 mOsm/kg. We diagnosed hypo-osmolar hyponatremia due to SIADH. Management included fluid restriction and then tolvaptan, which ultimately corrected the serum sodium to 134 mmol/L. As COVID-19 is a new infection, little is known regarding its impact on electrolyte imbalances. Our patient recovered from pneumonia, then later developed severe hyponatremia possibly secondary to the lasting effects of inflammation in her lungs.Abhinandan R. ChittalShiavax J. RaoPallavi LakraMary E. ZultyTaylor & Francis Grouparticlecovid-19hyponatremiasiadhhypotonic hyponatremiainterleukinInternal medicineRC31-1245ENJournal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 779-781 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 hyponatremia siadh hypotonic hyponatremia interleukin Internal medicine RC31-1245
spellingShingle	covid-19 hyponatremia siadh hypotonic hyponatremia interleukin Internal medicine RC31-1245 Abhinandan R. Chittal Shiavax J. Rao Pallavi Lakra Mary E. Zulty Asymptomatic hyponatremia precipitated by COVID-19 pneumonia
description	COVID-19, also known as SARS-CoV-2, which originated in China in late 2019, has spread rapidly resulting in a global pandemic. COVID-19 has been linked to many different clinical manifestations, including hyponatremia. The cause of hyponatremia in acute COVID-19 infection is speculated to be multifactorial, including syndrome of inappropriate antidiuretic hormone secretion (SIADH), thought to be a result of inflammatory cytokines (Interleukin-6) and/or related to the gastrointestinal symptoms of this infection. SIADH in the setting of COVID-19 pneumonia is an established complication of this disease. This is the case of an 81-year-old woman with a history of hypertension, on thiazide diuretic, initially presented after a fall in the setting of COVID-19 pneumonia. She was treated with remdesivir and dexamethasone and then discharged to a rehab facility with normal labwork, including a sodium of 137 mmol/L. Two weeks later, routine labwork identified hyponatremia of 111 mmol/L. Her vital signs were normal, she was euvolemic on exam and alert/oriented with no complaints. Investigations into the etiology of her hyponatremia included a urine sodium of 72 mmol/L, serum osmolality of 231 mOsm/kg, urine osmolality of 454 mOsm/kg. We diagnosed hypo-osmolar hyponatremia due to SIADH. Management included fluid restriction and then tolvaptan, which ultimately corrected the serum sodium to 134 mmol/L. As COVID-19 is a new infection, little is known regarding its impact on electrolyte imbalances. Our patient recovered from pneumonia, then later developed severe hyponatremia possibly secondary to the lasting effects of inflammation in her lungs.
format	article
author	Abhinandan R. Chittal Shiavax J. Rao Pallavi Lakra Mary E. Zulty
author_facet	Abhinandan R. Chittal Shiavax J. Rao Pallavi Lakra Mary E. Zulty
author_sort	Abhinandan R. Chittal
title	Asymptomatic hyponatremia precipitated by COVID-19 pneumonia
title_short	Asymptomatic hyponatremia precipitated by COVID-19 pneumonia
title_full	Asymptomatic hyponatremia precipitated by COVID-19 pneumonia
title_fullStr	Asymptomatic hyponatremia precipitated by COVID-19 pneumonia
title_full_unstemmed	Asymptomatic hyponatremia precipitated by COVID-19 pneumonia
title_sort	asymptomatic hyponatremia precipitated by covid-19 pneumonia
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/bab9b76c900e437581b5638b0f785389
work_keys_str_mv	AT abhinandanrchittal asymptomatichyponatremiaprecipitatedbycovid19pneumonia AT shiavaxjrao asymptomatichyponatremiaprecipitatedbycovid19pneumonia AT pallavilakra asymptomatichyponatremiaprecipitatedbycovid19pneumonia AT maryezulty asymptomatichyponatremiaprecipitatedbycovid19pneumonia
_version_	1718425505333510144

Asymptomatic hyponatremia precipitated by COVID-19 pneumonia

Ejemplares similares