Glaucoma related retinal oximetry: a technology update

Zhu Li Yap,1,2 Sushma Verma,2 Yi Fang Lee,1,2 Charles Ong,1,2 Aditi Mohla,1,2 Shamira A Perera1,2 1Singapore National Eye Center, 2Singapore Eye Research Institute, Singapore Abstract: There are two long-standing theories about the pathogenesis of glaucoma – barotrauma and the effect of...

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Autores principales:	Yap ZL, Verma S, Lee YF, Ong C, Mohla A, Perera SA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Retinal Oximetry Glaucoma Oxymap Retinal Vasculature Imaging Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/babc22e75ddb49369c15919b07da4f99
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spelling	oai:doaj.org-article:babc22e75ddb49369c15919b07da4f992021-12-02T02:15:21ZGlaucoma related retinal oximetry: a technology update1177-5483https://doaj.org/article/babc22e75ddb49369c15919b07da4f992018-01-01T00:00:00Zhttps://www.dovepress.com/glaucoma-related-retinal-oximetry-a-technology-update-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Zhu Li Yap,1,2 Sushma Verma,2 Yi Fang Lee,1,2 Charles Ong,1,2 Aditi Mohla,1,2 Shamira A Perera1,2 1Singapore National Eye Center, 2Singapore Eye Research Institute, Singapore Abstract: There are two long-standing theories about the pathogenesis of glaucoma – barotrauma and the effect of vascular hypoxia. Currently, it is still unknown whether diminished blood flow is the cause or result of glaucomatous atrophy of ganglion cells and the optic nerve. Though many other imaging techniques used to directly assess ocular blood flow have been well studied, they are limited by their inability to directly assess metabolism in the ocular tissues or measure the oxygen carrying capacity in the vessels. Retinal oximetry is a relatively novel, noninvasive imaging technique that reliably measures oxygen saturation levels in the retinal vessels, offering surrogate markers for the metabolic demands of the eye. The clinical significance of these measurements has not been well established. Thus, this review gives an overview of ocular imaging and current retinal oximetry techniques, while contextualizing the important oximetry studies that have investigated the vascular theory behind glaucoma. Keywords: retinal oximetry, glaucoma, Oxymap, retinal vasculature, glaucoma imagingYap ZLVerma SLee YFOng CMohla APerera SADove Medical PressarticleRetinal OximetryGlaucomaOxymapRetinal VasculatureImagingOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 79-84 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Retinal Oximetry Glaucoma Oxymap Retinal Vasculature Imaging Ophthalmology RE1-994
spellingShingle	Retinal Oximetry Glaucoma Oxymap Retinal Vasculature Imaging Ophthalmology RE1-994 Yap ZL Verma S Lee YF Ong C Mohla A Perera SA Glaucoma related retinal oximetry: a technology update
description	Zhu Li Yap,1,2 Sushma Verma,2 Yi Fang Lee,1,2 Charles Ong,1,2 Aditi Mohla,1,2 Shamira A Perera1,2 1Singapore National Eye Center, 2Singapore Eye Research Institute, Singapore Abstract: There are two long-standing theories about the pathogenesis of glaucoma – barotrauma and the effect of vascular hypoxia. Currently, it is still unknown whether diminished blood flow is the cause or result of glaucomatous atrophy of ganglion cells and the optic nerve. Though many other imaging techniques used to directly assess ocular blood flow have been well studied, they are limited by their inability to directly assess metabolism in the ocular tissues or measure the oxygen carrying capacity in the vessels. Retinal oximetry is a relatively novel, noninvasive imaging technique that reliably measures oxygen saturation levels in the retinal vessels, offering surrogate markers for the metabolic demands of the eye. The clinical significance of these measurements has not been well established. Thus, this review gives an overview of ocular imaging and current retinal oximetry techniques, while contextualizing the important oximetry studies that have investigated the vascular theory behind glaucoma. Keywords: retinal oximetry, glaucoma, Oxymap, retinal vasculature, glaucoma imaging
format	article
author	Yap ZL Verma S Lee YF Ong C Mohla A Perera SA
author_facet	Yap ZL Verma S Lee YF Ong C Mohla A Perera SA
author_sort	Yap ZL
title	Glaucoma related retinal oximetry: a technology update
title_short	Glaucoma related retinal oximetry: a technology update
title_full	Glaucoma related retinal oximetry: a technology update
title_fullStr	Glaucoma related retinal oximetry: a technology update
title_full_unstemmed	Glaucoma related retinal oximetry: a technology update
title_sort	glaucoma related retinal oximetry: a technology update
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/babc22e75ddb49369c15919b07da4f99
work_keys_str_mv	AT yapzl glaucomarelatedretinaloximetryatechnologyupdate AT vermas glaucomarelatedretinaloximetryatechnologyupdate AT leeyf glaucomarelatedretinaloximetryatechnologyupdate AT ongc glaucomarelatedretinaloximetryatechnologyupdate AT mohlaa glaucomarelatedretinaloximetryatechnologyupdate AT pererasa glaucomarelatedretinaloximetryatechnologyupdate
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Glaucoma related retinal oximetry: a technology update

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