Non-invasive optical control of endogenous Ca2+ channels in awake mice

Optogenetic applications in the brain of live animals often require the use of optic fibers due to poor tissue-penetration of blue light. Here the authors present monSTIM1, an improved high sensitivity optogenetic tool able to modulate Ca2+ signaling in the brain of awake mice using non-invasive lig...

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Autores principales:	Sungsoo Kim, Taeyoon Kyung, Jae-Hee Chung, Nury Kim, Sehoon Keum, Jinsu Lee, Hyerim Park, Ho Min Kim, Sangkyu Lee, Hee-Sup Shin, Won Do Heo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bac59abf3de24b728fa4249bd58add37
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spelling	oai:doaj.org-article:bac59abf3de24b728fa4249bd58add372021-12-02T15:33:32ZNon-invasive optical control of endogenous Ca2+ channels in awake mice10.1038/s41467-019-14005-42041-1723https://doaj.org/article/bac59abf3de24b728fa4249bd58add372020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14005-4https://doaj.org/toc/2041-1723Optogenetic applications in the brain of live animals often require the use of optic fibers due to poor tissue-penetration of blue light. Here the authors present monSTIM1, an improved high sensitivity optogenetic tool able to modulate Ca2+ signaling in the brain of awake mice using non-invasive light stimulation.Sungsoo KimTaeyoon KyungJae-Hee ChungNury KimSehoon KeumJinsu LeeHyerim ParkHo Min KimSangkyu LeeHee-Sup ShinWon Do HeoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sungsoo Kim Taeyoon Kyung Jae-Hee Chung Nury Kim Sehoon Keum Jinsu Lee Hyerim Park Ho Min Kim Sangkyu Lee Hee-Sup Shin Won Do Heo Non-invasive optical control of endogenous Ca2+ channels in awake mice
description	Optogenetic applications in the brain of live animals often require the use of optic fibers due to poor tissue-penetration of blue light. Here the authors present monSTIM1, an improved high sensitivity optogenetic tool able to modulate Ca2+ signaling in the brain of awake mice using non-invasive light stimulation.
format	article
author	Sungsoo Kim Taeyoon Kyung Jae-Hee Chung Nury Kim Sehoon Keum Jinsu Lee Hyerim Park Ho Min Kim Sangkyu Lee Hee-Sup Shin Won Do Heo
author_facet	Sungsoo Kim Taeyoon Kyung Jae-Hee Chung Nury Kim Sehoon Keum Jinsu Lee Hyerim Park Ho Min Kim Sangkyu Lee Hee-Sup Shin Won Do Heo
author_sort	Sungsoo Kim
title	Non-invasive optical control of endogenous Ca2+ channels in awake mice
title_short	Non-invasive optical control of endogenous Ca2+ channels in awake mice
title_full	Non-invasive optical control of endogenous Ca2+ channels in awake mice
title_fullStr	Non-invasive optical control of endogenous Ca2+ channels in awake mice
title_full_unstemmed	Non-invasive optical control of endogenous Ca2+ channels in awake mice
title_sort	non-invasive optical control of endogenous ca2+ channels in awake mice
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bac59abf3de24b728fa4249bd58add37
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Non-invasive optical control of endogenous Ca2+ channels in awake mice

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