Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea

Mechanoelectrical transduction channel (MET) current found in stereocilia of hair cells matures over the first postnatal week. Here the authors look at the contribution of transmembrane channel-like protein 1 and 2 (TMC1 and TMC2) to MET current during development of tonotopic gradients.

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Autores principales:	Maryline Beurg, Runjia Cui, Adam C. Goldring, Seham Ebrahim, Robert Fettiplace, Bechara Kachar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bacae67fdd6c42838993433203576aed
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spelling	oai:doaj.org-article:bacae67fdd6c42838993433203576aed2021-12-02T14:38:53ZVariable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea10.1038/s41467-018-04589-82041-1723https://doaj.org/article/bacae67fdd6c42838993433203576aed2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04589-8https://doaj.org/toc/2041-1723Mechanoelectrical transduction channel (MET) current found in stereocilia of hair cells matures over the first postnatal week. Here the authors look at the contribution of transmembrane channel-like protein 1 and 2 (TMC1 and TMC2) to MET current during development of tonotopic gradients.Maryline BeurgRunjia CuiAdam C. GoldringSeham EbrahimRobert FettiplaceBechara KacharNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maryline Beurg Runjia Cui Adam C. Goldring Seham Ebrahim Robert Fettiplace Bechara Kachar Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea
description	Mechanoelectrical transduction channel (MET) current found in stereocilia of hair cells matures over the first postnatal week. Here the authors look at the contribution of transmembrane channel-like protein 1 and 2 (TMC1 and TMC2) to MET current during development of tonotopic gradients.
format	article
author	Maryline Beurg Runjia Cui Adam C. Goldring Seham Ebrahim Robert Fettiplace Bechara Kachar
author_facet	Maryline Beurg Runjia Cui Adam C. Goldring Seham Ebrahim Robert Fettiplace Bechara Kachar
author_sort	Maryline Beurg
title	Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea
title_short	Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea
title_full	Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea
title_fullStr	Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea
title_full_unstemmed	Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea
title_sort	variable number of tmc1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/bacae67fdd6c42838993433203576aed
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Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea

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