Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea

Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea

Mechanoelectrical transduction channel (MET) current found in stereocilia of hair cells matures over the first postnatal week. Here the authors look at the contribution of transmembrane channel-like protein 1 and 2 (TMC1 and TMC2) to MET current during development of tonotopic gradients.

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Autores principales: Maryline Beurg, Runjia Cui, Adam C. Goldring, Seham Ebrahim, Robert Fettiplace, Bechara Kachar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/bacae67fdd6c42838993433203576aed
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