Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria
Antigens (Ags) with multivalent and repetitive structure elicit IgG production in a T-cell-independent manner. However, the mechanisms by which such T-cell-independent type-2 (TI-2) Ags induce IgG responses remain obscure. Here, we report that B-cell receptor (BCR) engagement with a TI-2 Ag but not...
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Auteurs principaux: | Saori Fukao, Kei Haniuda, Hiromasa Tamaki, Daisuke Kitamura |
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Format: | article |
Langue: | EN |
Publié: |
eLife Sciences Publications Ltd
2021
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Accès en ligne: | https://doaj.org/article/bacd8a89bd7e462fa3afbc6bbd3be148 |
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