Grip strength as a frailty diagnostic component in geriatric inpatients

Joanna Dudzińska-Griszek, Karolina Szuster, Jan Szewieczek Department of Geriatrics, School of Health Sciences in Katowice, Medical University of Silesia, Katowice, Poland Background: Frailty has emerged as a key medical syndrome predictive of comorbidity, disability, institutionalization and deat...

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Autores principales:	Dudzińska-Griszek J, Szuster K, Szewieczek J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	frailty grip strength geriatric inpatients cognitive function statin antidepressant. Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/bace39d81b4348cbac36eec3cf04e626
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spelling	oai:doaj.org-article:bace39d81b4348cbac36eec3cf04e6262021-12-02T03:45:29ZGrip strength as a frailty diagnostic component in geriatric inpatients1178-1998https://doaj.org/article/bace39d81b4348cbac36eec3cf04e6262017-07-01T00:00:00Zhttps://www.dovepress.com/grip-strength-as-a-frailty-diagnostic-component-in-geriatric-inpatient-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Joanna Dudzińska-Griszek, Karolina Szuster, Jan Szewieczek Department of Geriatrics, School of Health Sciences in Katowice, Medical University of Silesia, Katowice, Poland Background: Frailty has emerged as a key medical syndrome predictive of comorbidity, disability, institutionalization and death. As a component of the five frailty phenotype diagnostic criteria, patient grip strength deserves attention as a simple and objective measure of the frailty syndrome. The aim of this study was to assess conditions that influence grip strength in geriatric inpatients.Patients and methods: The study group consisted of 80 patients aged 78.6±7.0 years ( X ± SD), with 68.8% women, admitted to the Department of Geriatrics. A comprehensive geriatric assessment was complemented with assessment for the frailty phenotype as described by Fried et al for all patients in the study group. Functional assessment included Barthel Index of Activities of Daily Living (Barthel Index), Instrumental Activities of Daily Living Scale and Mini-Mental State Examination.Results: Three or more frailty criteria were positive in 32 patients (40%), while 56 subjects (70%) fulfilled the frailty criterion of weakness (grip strength test). Multivariate linear regression analysis revealed that two independent measures showed positive association with grip strength – Mini-Mental State Examination score (β=0.239; P=0.001) and statin use (β=0.213; P=0.002) – and four independent measures were negatively associated with grip strength – female sex (β=–0.671; P<0.001), C-reactive protein (β=–0.253; P<0.001), prior myocardial infarction (β=–0.190; P=0.006) and use of an antidepressant (β=–0.163; P=0.018). Low physical activity was identified as the only independent qualitative frailty component associated with 2-year mortality in multivariate logistic regression analysis after adjustment for age and sex (odds ratio =6.000; 95% CI =1.357–26.536; P=0.018).Conclusion: Cognitive function, somatic comorbidity and medical treatment affect grip strength as a measure of physical frailty in geriatric inpatients. Grip strength was not predictive of 2-year mortality in this group. Keywords: frailty, cognitive function, statin, antidepressant, physical activity, mortalityDudzińska-Griszek JSzuster KSzewieczek JDove Medical Pressarticlefrailtygrip strengthgeriatric inpatientscognitive functionstatinantidepressant.GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 12, Pp 1151-1157 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	frailty grip strength geriatric inpatients cognitive function statin antidepressant. Geriatrics RC952-954.6
spellingShingle	frailty grip strength geriatric inpatients cognitive function statin antidepressant. Geriatrics RC952-954.6 Dudzińska-Griszek J Szuster K Szewieczek J Grip strength as a frailty diagnostic component in geriatric inpatients
description	Joanna Dudzińska-Griszek, Karolina Szuster, Jan Szewieczek Department of Geriatrics, School of Health Sciences in Katowice, Medical University of Silesia, Katowice, Poland Background: Frailty has emerged as a key medical syndrome predictive of comorbidity, disability, institutionalization and death. As a component of the five frailty phenotype diagnostic criteria, patient grip strength deserves attention as a simple and objective measure of the frailty syndrome. The aim of this study was to assess conditions that influence grip strength in geriatric inpatients.Patients and methods: The study group consisted of 80 patients aged 78.6±7.0 years ( X ± SD), with 68.8% women, admitted to the Department of Geriatrics. A comprehensive geriatric assessment was complemented with assessment for the frailty phenotype as described by Fried et al for all patients in the study group. Functional assessment included Barthel Index of Activities of Daily Living (Barthel Index), Instrumental Activities of Daily Living Scale and Mini-Mental State Examination.Results: Three or more frailty criteria were positive in 32 patients (40%), while 56 subjects (70%) fulfilled the frailty criterion of weakness (grip strength test). Multivariate linear regression analysis revealed that two independent measures showed positive association with grip strength – Mini-Mental State Examination score (β=0.239; P=0.001) and statin use (β=0.213; P=0.002) – and four independent measures were negatively associated with grip strength – female sex (β=–0.671; P<0.001), C-reactive protein (β=–0.253; P<0.001), prior myocardial infarction (β=–0.190; P=0.006) and use of an antidepressant (β=–0.163; P=0.018). Low physical activity was identified as the only independent qualitative frailty component associated with 2-year mortality in multivariate logistic regression analysis after adjustment for age and sex (odds ratio =6.000; 95% CI =1.357–26.536; P=0.018).Conclusion: Cognitive function, somatic comorbidity and medical treatment affect grip strength as a measure of physical frailty in geriatric inpatients. Grip strength was not predictive of 2-year mortality in this group. Keywords: frailty, cognitive function, statin, antidepressant, physical activity, mortality
format	article
author	Dudzińska-Griszek J Szuster K Szewieczek J
author_facet	Dudzińska-Griszek J Szuster K Szewieczek J
author_sort	Dudzińska-Griszek J
title	Grip strength as a frailty diagnostic component in geriatric inpatients
title_short	Grip strength as a frailty diagnostic component in geriatric inpatients
title_full	Grip strength as a frailty diagnostic component in geriatric inpatients
title_fullStr	Grip strength as a frailty diagnostic component in geriatric inpatients
title_full_unstemmed	Grip strength as a frailty diagnostic component in geriatric inpatients
title_sort	grip strength as a frailty diagnostic component in geriatric inpatients
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/bace39d81b4348cbac36eec3cf04e626
work_keys_str_mv	AT dudzinskagriszekj gripstrengthasafrailtydiagnosticcomponentingeriatricinpatients AT szusterk gripstrengthasafrailtydiagnosticcomponentingeriatricinpatients AT szewieczekj gripstrengthasafrailtydiagnosticcomponentingeriatricinpatients
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Grip strength as a frailty diagnostic component in geriatric inpatients

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