Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics

Methods to study conformational changes in biomolecules are limited in resolution and require labelling or other modifications of target analytes. Here the authors present a label-free, microwave microfluidic approach to detect conformational changes of DNA nanostructures based on ionic conductivity...

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Autores principales:	Angela C. Stelson, Minghui Liu, Charles A. E. Little, Christian J. Long, Nathan D. Orloff, Nicholas Stephanopoulos, James C. Booth
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bad0e280e28c4df1bd9cab8f703da332
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spelling	oai:doaj.org-article:bad0e280e28c4df1bd9cab8f703da3322021-12-02T14:39:40ZLabel-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics10.1038/s41467-019-09017-z2041-1723https://doaj.org/article/bad0e280e28c4df1bd9cab8f703da3322019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09017-zhttps://doaj.org/toc/2041-1723Methods to study conformational changes in biomolecules are limited in resolution and require labelling or other modifications of target analytes. Here the authors present a label-free, microwave microfluidic approach to detect conformational changes of DNA nanostructures based on ionic conductivity.Angela C. StelsonMinghui LiuCharles A. E. LittleChristian J. LongNathan D. OrloffNicholas StephanopoulosJames C. BoothNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Angela C. Stelson Minghui Liu Charles A. E. Little Christian J. Long Nathan D. Orloff Nicholas Stephanopoulos James C. Booth Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics
description	Methods to study conformational changes in biomolecules are limited in resolution and require labelling or other modifications of target analytes. Here the authors present a label-free, microwave microfluidic approach to detect conformational changes of DNA nanostructures based on ionic conductivity.
format	article
author	Angela C. Stelson Minghui Liu Charles A. E. Little Christian J. Long Nathan D. Orloff Nicholas Stephanopoulos James C. Booth
author_facet	Angela C. Stelson Minghui Liu Charles A. E. Little Christian J. Long Nathan D. Orloff Nicholas Stephanopoulos James C. Booth
author_sort	Angela C. Stelson
title	Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics
title_short	Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics
title_full	Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics
title_fullStr	Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics
title_full_unstemmed	Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics
title_sort	label-free detection of conformational changes in switchable dna nanostructures with microwave microfluidics
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/bad0e280e28c4df1bd9cab8f703da332
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Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics

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