Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.

Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.

The ability of Plasmodium falciparum parasitized RBC (pRBC) to form rosettes with normal RBC is linked to the virulence of the parasite and RBC polymorphisms that weaken rosetting confer protection against severe malaria. The adhesin PfEMP1 mediates the binding and specific antibodies prevent seques...

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Main Authors: Davide Angeletti, Letusa Albrecht, Karin Blomqvist, María Del Pilar Quintana, Tahmina Akhter, Susanna M Bächle, Alan Sawyer, Tatyana Sandalova, Adnane Achour, Mats Wahlgren, Kirsten Moll
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/bad2c7e4e2a246a4811d5a604e7a3909
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