Chromatin topology is coupled to Polycomb group protein subnuclear organization

Polycomb Group (PcG) proteins regulate gene expression and genome architecture. Using super-resolution microscopy and molecular simulations, Waniet al. describe the organization of PcG proteins into hundreds of nano-scale protein clusters and suggest these clusters shape genome architecture.

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Autores principales:	Ajazul H. Wani, Alistair N. Boettiger, Patrick Schorderet, Ayla Ergun, Christine Münger, Ruslan I. Sadreyev, Xiaowei Zhuang, Robert E. Kingston, Nicole J. Francis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bad9f905cda545d68fdd91a193c22c33
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spelling	oai:doaj.org-article:bad9f905cda545d68fdd91a193c22c332021-12-02T17:31:35ZChromatin topology is coupled to Polycomb group protein subnuclear organization10.1038/ncomms102912041-1723https://doaj.org/article/bad9f905cda545d68fdd91a193c22c332016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10291https://doaj.org/toc/2041-1723Polycomb Group (PcG) proteins regulate gene expression and genome architecture. Using super-resolution microscopy and molecular simulations, Waniet al. describe the organization of PcG proteins into hundreds of nano-scale protein clusters and suggest these clusters shape genome architecture.Ajazul H. WaniAlistair N. BoettigerPatrick SchorderetAyla ErgunChristine MüngerRuslan I. SadreyevXiaowei ZhuangRobert E. KingstonNicole J. FrancisNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ajazul H. Wani Alistair N. Boettiger Patrick Schorderet Ayla Ergun Christine Münger Ruslan I. Sadreyev Xiaowei Zhuang Robert E. Kingston Nicole J. Francis Chromatin topology is coupled to Polycomb group protein subnuclear organization
description	Polycomb Group (PcG) proteins regulate gene expression and genome architecture. Using super-resolution microscopy and molecular simulations, Waniet al. describe the organization of PcG proteins into hundreds of nano-scale protein clusters and suggest these clusters shape genome architecture.
format	article
author	Ajazul H. Wani Alistair N. Boettiger Patrick Schorderet Ayla Ergun Christine Münger Ruslan I. Sadreyev Xiaowei Zhuang Robert E. Kingston Nicole J. Francis
author_facet	Ajazul H. Wani Alistair N. Boettiger Patrick Schorderet Ayla Ergun Christine Münger Ruslan I. Sadreyev Xiaowei Zhuang Robert E. Kingston Nicole J. Francis
author_sort	Ajazul H. Wani
title	Chromatin topology is coupled to Polycomb group protein subnuclear organization
title_short	Chromatin topology is coupled to Polycomb group protein subnuclear organization
title_full	Chromatin topology is coupled to Polycomb group protein subnuclear organization
title_fullStr	Chromatin topology is coupled to Polycomb group protein subnuclear organization
title_full_unstemmed	Chromatin topology is coupled to Polycomb group protein subnuclear organization
title_sort	chromatin topology is coupled to polycomb group protein subnuclear organization
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/bad9f905cda545d68fdd91a193c22c33
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Chromatin topology is coupled to Polycomb group protein subnuclear organization

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